High density lipoproteins and coronary heart disease

PJ Barter, KA Rye - Atherosclerosis, 1996 - Elsevier
An inverse relationship between the concentration of high density lipoprotein (HDL)
cholesterol and the development of coronary heart disease (CHD) is well established. It is …

[HTML][HTML] The HDL hypothesis: does high-density lipoprotein protect from atherosclerosis?

M Vergeer, AG Holleboom, JJP Kastelein… - Journal of lipid …, 2010 - ASBMB
There is unequivocal evidence of an inverse association between plasma high-density
lipoprotein (HDL) cholesterol concentrations and the risk of cardiovascular disease, a …

High density lipoproteins (HDLs) and atherosclerosis; the unanswered questions

P Barter, J Kastelein, A Nunn, R Hobbs, FFE Board - Atherosclerosis, 2003 - Elsevier
The concentration of high density lipoprotein-cholesterol (HDL-C) has been found
consistently to be a powerful negative predictor of premature coronary heart disease (CHD) …

Atheroprotective effects of high-density lipoproteins

G Assmann, JR Nofer - Annual review of medicine, 2003 - annualreviews.org
Observational studies provide overwhelming evidence that a low high-density lipoprotein
(HDL)–cholesterol level increases the risk of coronary events, both in healthy subjects and …

High-density lipoprotein cholesterol and coronary artery disease: survey of the evidence

BM Rifkind - The American journal of cardiology, 1990 - Elsevier
The epidemiologic evidence linking high-density lipoprotein (HDL) levels with coronary
artery disease (CAD) is persuasive. Case-control studies have shown CAD patients to have …

High-density lipoprotein and atherosclerosis regression: evidence from preclinical and clinical studies

JE Feig, B Hewing, JD Smith, SL Hazen… - Circulation …, 2014 - Am Heart Assoc
High-density lipoprotein (HDL) particles transport (among other molecules) cholesterol (HDL-
C). In epidemiological studies, plasma HDL-C levels have an inverse relationship to the risk …

Assessing low levels of high-density lipoprotein cholesterol as a risk factor in coronary heart disease: a working group report and update

AM Gotto, EA Brinton - Journal of the American College of Cardiology, 2004 - jacc.org
Clinical data show that a 1% increase in serum concentrations of high-density lipoprotein
cholesterol (HDL-C) can decrease cardiovascular risk by 2% to 3%. Therefore, mechanisms …

Molecular mechanisms of vascular effects of high‐density lipoprotein: alterations in cardiovascular disease

C Besler, TF Lüscher, U Landmesser - EMBO molecular medicine, 2012 - embopress.org
Low high‐density lipoprotein (HDL)‐cholesterol levels are associated with an increased risk
of coronary artery disease (CAD) and myocardial infarction, which has triggered the …

High-density lipoproteins and atherosclerosis

DJ Rader - The American journal of cardiology, 2002 - Elsevier
High-density lipoproteins (HDLs) are strongly related to risk of atherosclerotic cardiovascular
disease. Low levels of HDL cholesterol are a major cardiovascular risk factor, and …

[HTML][HTML] High-density lipoprotein (HDL) functionality and its relevance to atherosclerotic cardiovascular disease

CE Kosmas, I Martinez, A Sourlas, KV Bouza… - Drugs in …, 2018 - ncbi.nlm.nih.gov
Several prospective epidemiological studies have shown that there is a clear inverse
relationship between serum high-density lipoprotein-cholesterol (HDL-C) concentrations …