All implanted biomaterials are targets of the host's immune system. While the host
inflammatory response was once considered a detrimental force to be blunted or avoided, in …

There is a tremendous need for organs and tissues to replace those lost due to diseases or
trauma. In theory, transplanting cells on biomaterial matrices can create functional tissue. A …

Stem cells have been extensively used in regenerative medicine and tissue engineering;
however, they often lose their functionality because of the inflammatory microenvironment …

The lymphatic system is essential for tissue regeneration and repair due to its pivotal role in
resolving inflammation, immune cell surveillance, lipid transport, and maintaining tissue …

Endogenous regeneration aims to rebuild and reinstate tissue function through enlisting
natural self-repairing processes. Promoting endogenous regeneration by reducing tissue …

Insights into the use of cellular therapeutics, extracellular vesicles (EVs), and tissue
engineering strategies for regenerative medicine applications are continually emerging with …

Strategies to enhance, suppress, or qualitatively shape the immune response are of
importance for diverse biomedical applications, such as the development of new vaccines …

Tissue engineering is increasingly based on recapitulating human physiology, through
integration of biological principles into engineering designs. In spite of all progress in …

The promise of tissue engineering and regenerative medicine to reduce the burden of
disease and improve quality of life are widely acknowledged. Traditional tissue engineering …

Cytokine signaling is critical to a range of biological processes including cell development,
tissue repair, aging, and immunity. In addition to acting as key signal mediators of the …