Purpose Poorly characterized macromolecular (MM) and baseline artefacts are known to
reduce metabolite quantitation accuracy in 1H MR spectroscopic imaging (MRSI). Increasing …

Purpose To determine the test‐retest reproducibility of neurochemical concentrations
obtained with a highly optimized, short‐echo, single‐voxel proton MR spectroscopy (MRS) …

Abstract 1 H Magnetic Resonance Spectroscopy (MRS) is an important non-invasive tool for
measuring brain metabolism, with numerous applications in the neuroscientific and clinical …

The purpose of the current study was to develop a novel single‐voxel MR spectroscopy
acquisition scheme to simultaneously determine metabolite‐specific concentrations and …

Magnetic resonance spectroscopy (MRS) is an important clinical imaging method for
diagnosis of diseases. MRS spectrum is used to observe the signal intensity of metabolites …

Abstract Magnetic Resonance Spectroscopic Imaging (MRSI) is a clinical imaging modality
for measuring tissue metabolite levels in-vivo. An accurate estimation of spectral parameters …

Quantification of metabolites from magnetic resonance spectra (MRS) has many
applications in medicine and psychology, but remains a challenging task despite …

Background J‐coupled metabolites are often measured at a predetermined echo time in the
presence of macromolecule signals, which complicates the measurement of metabolite T1 …

It has been previously established that inappropriately modeled spectral baselines can
confound metabolite concentration estimates by in vivo 1 H MRS even while contributing to …

Purpose Accurate baseline modeling is essential for reliable MRS analysis and
interpretation—particularly at short echo‐times, where enhanced metabolite information …