Emerging targets in neurodegeneration: new opportunities for Alzheimer's disease treatment?
A Rampa, S Gobbi, F Belluti… - Current Topics in Medicinal …, 2013 - ingentaconnect.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder of the brain
associated with memory impairment, progressive cognitive decline and changes in …
associated with memory impairment, progressive cognitive decline and changes in …
Novel therapeutic strategies for dementia
R Cacabelos, C Torrellas, I Carrera… - CNS & Neurological …, 2016 - ingentaconnect.com
Dementia represents a major problem of health and disability, with a relevant economic
impact on our society. Despite important advances in pathogenesis, diagnosis and …
impact on our society. Despite important advances in pathogenesis, diagnosis and …
Recent Advancements in the Treatment of Alzheimer's Disease: A Multitarget-directed Ligand Approach
S Kumar, A Mahajan, R Ambatwar… - Current Medicinal …, 2024 - ingentaconnect.com
Alzheimer's disease (AD) is a neurodegenerative disease and one of the leading causes of
progressive dementia, affecting 50 million people worldwide. Many pathogenic processes …
progressive dementia, affecting 50 million people worldwide. Many pathogenic processes …
Current and emerging therapies for Alzheimer's disease
HB Nygaard - Clinical therapeutics, 2013 - Elsevier
Alzheimer's disease (AD) is a devastating neurodegenerative disorder, with a rapidly
increasing worldwide prevalence. Although no cure for AD has yet been found, substantial …
increasing worldwide prevalence. Although no cure for AD has yet been found, substantial …
Therapeutic opportunities in Alzheimer disease: one for all or all for one?
MW Marlatt, KM Webber, PI Moreira… - Current medicinal …, 2005 - ingentaconnect.com
In recent years, Alzheimer disease (AD) has received great attention as an incurable and
fatal disease that threatens the lives of aging individuals. Debates regarding areas of …
fatal disease that threatens the lives of aging individuals. Debates regarding areas of …
Neurodegenerative pathways in Alzheimer's disease: a review
Alzheimer's disease (AD) is a complex neurodegenerative disease that leads to insidious
deterioration of brain functions and is considered the sixth leading cause of death in the …
deterioration of brain functions and is considered the sixth leading cause of death in the …
Introduction to special issue on Alzheimer's disease
MS Wolfe - Journal of Medicinal Chemistry, 2012 - ACS Publications
One of the greatest challenges facing medicinal chemists in the 21st century is the discovery
and development of compounds for the prevention, treatment, and diagnosis of Alzheimer's …
and development of compounds for the prevention, treatment, and diagnosis of Alzheimer's …
Current trends in the development of drugs for the treatment of Alzheimer's disease and their clinical trials
SO Bachurin, EV Bovina, AA Ustyugov - … Chemistry: Research and …, 2018 - bmc-rm.org
Intracellular and extracellular accumulation of fibrillary proteins, beta-amyloid and
hyperphosphorylated Tau, in patients with Alzheimer's disease (AD) leads to chronic and …
hyperphosphorylated Tau, in patients with Alzheimer's disease (AD) leads to chronic and …
Alzheimer's Disease: Development of Disease-Modifying Treatments Is the Challenge for Our Generation
CW Lindsley - ACS chemical neuroscience, 2012 - ACS Publications
Medicinal Chemistry Letters to highlight advances in the pharmacology, medicinal
chemistry, and therapeutic strategies currently under development for Alzheimer's disease …
chemistry, and therapeutic strategies currently under development for Alzheimer's disease …
Multifaceted Alzheimer's disease: Building a roadmap for advancement of novel therapies
D Kaur, T Behl, A Sehgal, S Singh, N Sharma… - Neurochemical …, 2021 - Springer
Alzheimer's disease (AD) is one of the most prevailing neurodegenerative disorders of
elderly humans associated with cognitive damage. Biochemical, epigenetic, and …
elderly humans associated with cognitive damage. Biochemical, epigenetic, and …