Nutrient‐dependent enhancement of rectal sensitivity in irritable bowel syndrome (IBS)

M Simrén, P Agerforz, ES Björnsson… - …, 2007 - Wiley Online Library
Food‐related gastrointestinal symptoms are common in irritable bowel syndrome (IBS), but
the mechanisms behind this are unclear. Enhanced colorectal sensitivity after duodenal lipid …

An exaggerated sensory component of the gastrocolonic response in patients with irritable bowel syndrome

M Simren, H Abrahamsson, ES Björnsson - Gut, 2001 - gut.bmj.com
BACKGROUND/AIMS Visceral hypersensitivity is a feature of the irritable bowel syndrome
(IBS). Postprandial symptoms are common in these patients. The effects of nutrients on …

Lipid-induced colonic hypersensitivity in the irritable bowel syndrome: the role of bowel habit, sex, and psychologic factors

M Simrén, H Abrahamsson, ES Björnsson - Clinical Gastroenterology and …, 2007 - Elsevier
Background & Aims: Duodenal lipid infusion increases colonic hypersensitivity in irritable
bowel syndrome (IBS). Whether this is affected by bowel habit, psychologic factors, or sex is …

Visceral sensitivity and symptoms in patients with constipation-or diarrhea-predominant irritable bowel syndrome (IBS): effect of a low-fat intraduodenal infusion

MP Caldarella, A Milano, F Laterza… - Official journal of the …, 2005 - journals.lww.com
BACKGROUND Visceral hypersensitivity is common in Irritable Bowel Syndrome (IBS)
patients, and symptoms exacerbate postprandially. Yet the effects of nutrients on visceral …

Physiological modulation of jejunal sensitivity in health and in irritable bowel syndrome

PR Evans, JE Kellow - Official journal of the American College of …, 1998 - journals.lww.com
Objectives: In irritable bowel syndrome (IBS), enhanced sensitivity to distention of the small
bowel has been demonstrated. We sought to compare, in healthy subjects and in IBS …

Interaction between preprandial and postprandial rectal sensory and motor abnormalities in IBS

H Törnblom, L Van Oudenhove, J Tack, M Simrén - Gut, 2014 - gut.bmj.com
Background and aims Rectal sensory and motor interactions in patients with IBS have not
been studied in detail. The aim of this study was to evaluate fasting and postprandial rectal …

Is the colonic response to food different in IBS in contrast to simple constipation or diarrhea without abdominal pain?

M Bouchoucha, G Devroede, JJ Raynaud… - Digestive diseases and …, 2011 - Springer
Background Colonic response to food (CRF) is abnormal in irritable bowel syndrome (IBS)
patients. Aims The aim of this study was to compare CRF in patients who complain of …

Does meal ingestion enhance sensitivity of visceroperception assessment in irritable bowel syndrome?

S Ludidi, JM Conchillo, D Keszthelyi… - …, 2012 - Wiley Online Library
Background Visceral hypersensitivity is frequently observed in irritable bowel syndrome
(IBS). Previous studies have shown that administration of a meal can aggravate symptoms …

Dimensions of gut dysfunction in irritable bowel syndrome: altered sensory function

F Azpiroz - Canadian Journal of Gastroenterology and …, 1999 - Wiley Online Library
Growing evidence suggests that symptoms in patients with irritable bowel syndrome (IBS)
may be due to a visceral sensory dysfunction. Specifically, it has been shown that patients …

Sensory dysfunction and the irritable bowel syndrome

LA Houghton - Best Practice & Research Clinical Gastroenterology, 1999 - Elsevier
Dysfunction of the sensory system of the gut is now generally believed to be important in the
pathophysiology of irritable bowel syndrome (IBS). This disturbance may well account for …