Neurons affected in Parkinson's disease (PD) experience mitochondrial dysfunction and
bioenergetic deficits that occur early and promote the disease-related α-synucleinopathy …

Being major sources of reactive oxygen species (ROS), mitochondrial structures are
exposed to high concentrations of ROS and might therefore be particularly susceptible to …

Although the pathogenesis of neurodegenerative diseases is still widely unclear, various
mechanisms have been proposed and several pieces of evidence are supportive for an …

Alzheimer's disease (AD) is a progressive neurodegenerative disease, characterized by
memory loss and multiple cognitive impairments. With the increased aging population, AD is …

Mitochondria are crucial regulators of energy metabolism and apoptotic pathways and have
been closely linked to the pathogenesis of neurodegenerative disorders. In this review we …

Mitochondrial dysfunction is one of the earliest and most prominent features in the brains of
Alzheimer's disease (AD) patients. Recent studies suggest that mitochondrial dysfunction …

Alzheimer's disease (AD) is a progressive neurodegenerative disease that affects a
staggering percentage of the aging population and causes memory loss and cognitive …

Mitochondrial dysfunction is a central aspect of aging and neurodegenerative diseases,
including Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and …

Macroautophagy is a cellular process by which cytosolic components and organelles are
degraded in double-membrane bound structures upon fusion with lysosomes. A pathway for …

Mitochondrial dysfunctions are supposed to be responsible for many neurodegenerative
diseases dominating in Alzheimer's disease (AD), Parkinson's disease (PD), and …