Adipokines, insulin resistance, metabolic syndrome, and breast cancer recurrence: a cohort study

SW Oh, CY Park, ES Lee, YS Yoon, ES Lee… - Breast Cancer …, 2011 - Springer
Introduction Several in vitro studies have suggested the effects of adipokines and insulin
resistance on breast cancer cell proliferation and survival. However, little is known about the …

Associations of insulin resistance and adiponectin with mortality in women with breast cancer

C Duggan, ML Irwin, L Xiao, KD Henderson… - Journal of clinical …, 2011 - ascopubs.org
Purpose Overweight or obese breast cancer patients have a worse prognosis compared
with normal-weight patients. This may be attributed to hyperinsulinemia and dysregulation of …

Prognostic effect of circulating adiponectin in a randomized 2× 2 trial of low-dose tamoxifen and fenretinide in premenopausal women at risk for breast cancer

D Macis, S Gandini, A Guerrieri-Gonzaga… - Journal of clinical …, 2012 - ascopubs.org
Purpose Adipokines are linked to obesity and insulin sensitivity and have recently been
related to breast cancer risk and prognosis. We investigated the associations of plasma …

Obesity, adipocytokines, and insulin resistance in breast cancer

DP Rose, D Komninou, GD Stephenson - Obesity reviews, 2004 - Wiley Online Library
The adipocytokines are biologically active polypeptides that are produced either exclusively
or substantially by the adipocytes, and act by endocrine, paracrine, and autocrine …

Adiponectin and breast cancer risk

C Mantzoros, E Petridou, N Dessypris… - The Journal of …, 2004 - academic.oup.com
Adiponectin, an adipocyte-secreted hormone, is closely and inversely associated with
insulin resistance and was recently found to be inversely and independently associated with …

Do adipokines underlie the association between known risk factors and breast cancer among a cohort of United States women?

MM Gaudet, RT Falk, GL Gierach, JV Lacey Jr… - Cancer …, 2010 - Elsevier
Introduction: Obesity is a well-established risk factor for postmenopausal breast cancer, but
mechanisms underlying the association are unclear. Adipocyte-derived, cytokine-like …

Adipokines in plasma and breast tissues: associations with breast cancer risk factors

AA Llanos, RG Dumitrescu, C Marian… - … , biomarkers & prevention, 2012 - AACR
Background: Blood adipokines are associated with breast cancer risk; however, blood–
breast adipokine correlations and factors that explain variation in adipokines are unknown …

Effects of adiponectin and leptin co-treatment on human breast cancer cell growth

KJ Nkhata, A Ray, TF Schuster… - Oncology …, 2009 - spandidos-publications.com
Obesity is a risk factor for postmenopausal breast cancer (BC), but the specific mechanisms
for this relationship are not well understood. Studies on adipocyte-derived adiponectin and …

Total and High-Molecular-Weight Adiponectin in Breast Cancer: In Vitro and in Vivo Studies

A Körner, K Pazaitou-Panayiotou… - The Journal of …, 2007 - academic.oup.com
Background: Obesity is a major risk factor for breast cancer. We hypothesized that obesity-
induced decreases in total and/or high-molecular-weight (HMW) adiponectin levels may …

Anthropometric measures, plasma adiponectin, and breast cancer risk

YF Tian, CH Chu, MH Wu, CL Chang… - Endocrine-related …, 2007 - erc.bioscientifica.com
Adiponectin is a peptide hormone secreted exclusively by adipocytes, and obesity is an
established risk factor for breast cancer. We have, thus, evaluated the associations of …