Background. Artemisinin-based combination therapies (ACTs) have been widely adopted as
first-line agents to treat uncomplicated falciparum malaria due to their activity against …

While significant advances have been made in the prevention and treatment of malaria in
recent years, these successes continue to fall short of the World Health Organization (WHO) …

Background Gametocytes are responsible for transmission of malaria from human to
mosquito. Artemisinin combination therapy (ACT) reduces post-treatment gametocyte …

Background Artemisinin combination therapies (ACT), which are increasingly being
introduced for treatment of Plasmodium falciparum malaria, are more effective against …

Artemisinin-based combination therapies (ACTs) and trimethoprim-sulfamethoxazole (TS)
prophylaxis are important tools for malaria control, but there are concerns about their effect …

Background Primaquine is an important gametocytocidal drug that is combined with
conventional malaria treatment for prevention of Plasmodium falciparum malaria …

Artemisinin combination therapies eliminate immature Plasmodium falciparum gametocytes
but not mature gametocytes, which may persist for up to 1 month posttreatment. A single …

Artemisinin-based combination therapies (ACTs) are currently considered the first-line
treatments for uncomplicated Plasmodium falciparum malaria. Among these, artemether …

Abstract Background Since the World Health Organization recommended single low-dose
(0.25 mg/kg) primaquine (PQ) in combination with artemisinin-based combination therapies …

Background: Most malaria-endemic countries use artemisinin-based combination therapy
(ACT) as their first-line treatment. ACTs are known to be highly effective on asexual stages of …