Role of isavuconazole in the treatment of invasive fungal infections
DT Wilson, VP Dimondi, SW Johnson… - … and clinical risk …, 2016 - Taylor & Francis
Despite recent advances in both diagnosis and prevention, the incidence of invasive fungal
infections continues to rise. Available antifungal agents to treat invasive fungal infections …
infections continues to rise. Available antifungal agents to treat invasive fungal infections …
Isavuconazole: mechanism of action, clinical efficacy, and resistance
M Ellsworth, L Ostrosky-Zeichner - Journal of fungi, 2020 - mdpi.com
Increasing incidence of invasive fungal infections combined with a growing population of
immunocompromised hosts has created a rising need for antifungal agents. Isavuconazole …
immunocompromised hosts has created a rising need for antifungal agents. Isavuconazole …
Isavuconazole: a new option for the management of invasive fungal infections
Objective: To review the pharmacology, chemistry, in vitro susceptibility, pharmacokinetics,
clinical efficacy, safety, tolerability, dosage, and administration of isavuconazole, a triazole …
clinical efficacy, safety, tolerability, dosage, and administration of isavuconazole, a triazole …
New perspectives on antimicrobial agents: isavuconazole
JS Lewis, NP Wiederhold, M Hakki… - Antimicrobial agents …, 2022 - Am Soc Microbiol
Isavuconazole is the newest of the clinically available advanced generation triazole
antifungals and is active against a variety of yeasts, molds, and dimorphic fungi. Its current …
antifungals and is active against a variety of yeasts, molds, and dimorphic fungi. Its current …
Isavuconazole: a new and promising antifungal triazole for the treatment of invasive fungal infections
J Guinea, E Bouza - Future Microbiology, 2008 - Taylor & Francis
Invasive fungal infections (IFIs) are an important cause of morbidity and mortality.
Isavuconazole (BAL4815) is a promising novel broad-spectrum triazole in late-stage clinical …
Isavuconazole (BAL4815) is a promising novel broad-spectrum triazole in late-stage clinical …
Isavuconazole: a review in invasive aspergillosis and mucormycosis
M Shirley, LJ Scott - Drugs, 2016 - Springer
Isavuconazole is a second-generation triazole with activity against a broad spectrum of
clinically important fungi. Its water-soluble prodrug, isavuconazonium sulfate (Cresemba®) …
clinically important fungi. Its water-soluble prodrug, isavuconazonium sulfate (Cresemba®) …
Evaluation of the pharmacokinetics and clinical utility of isavuconazole for treatment of invasive fungal infections
J Livermore, W Hope - Expert Opinion on Drug Metabolism & …, 2012 - Taylor & Francis
Introduction: Invasive fungal infections remain a leading cause of infectious morbidity and
mortality in immunocompromised patients. There are relatively few effective antifungal …
mortality in immunocompromised patients. There are relatively few effective antifungal …
Isavuconazole: pharmacology, pharmacodynamics, and current clinical experience with a new triazole antifungal agent
Coinciding with the continually increasing population of immunocompromised patients
worldwide, the incidence of invasive fungal infections has grown over the past 4 decades …
worldwide, the incidence of invasive fungal infections has grown over the past 4 decades …
Isavuconazonium sulfate: a triazole prodrug for invasive fungal infections
D Murrell, JB Bossaer, R Carico… - … Journal of Pharmacy …, 2017 - academic.oup.com
Objective To review the place in therapy of isavuconazole, the active metabolite of
isavuconazonium sulfate, via a review of the available literature on drug chemistry, spectrum …
isavuconazonium sulfate, via a review of the available literature on drug chemistry, spectrum …
Isavuconazole treatment in a mixed patient cohort with invasive fungal infections: outcome, tolerability and clinical implications of isavuconazole plasma …
C Zurl, M Waller, F Schwameis, T Muhr, N Bauer… - Journal of Fungi, 2020 - mdpi.com
Isavuconazole (ISA) is a triazole antifungal agent recommended for treatment of invasive
aspergillosis or mucormycosis. The objective of this study was to evaluate ISA levels in a …
aspergillosis or mucormycosis. The objective of this study was to evaluate ISA levels in a …