To determine whether apoptotic and necrotic myocyte cell death occur acutely and
chronically after infarction, the formation of DNA strand breaks and the localization of myosin …

Programmed cell death in the myocardium has been linked to ischemia reperfusion injury as
well as to excessive mechanical forces associated with increases in ventricular loading …

The most effective way to limit myocardial ischemic necrosis is reperfusion, but reperfusion
itself may result in tissue injury, which has been difficult to separate from ischemic injury …

Background In general, myocyte death in myocardial infarctions (MIs) is attributed to
necrosis, but recently the involvement of apoptosis has been suggested. The ratio of bcl-2 …

Background After reopening of the infarct-related coronary artery, cardiomyocytes continue
to die during reperfusion. The mechanisms of cell death have been subject to debate. We …

Acute ischemia followed by prolonged reperfusion has been shown to induce cardiomyocyte
apoptosis. In this report, we demonstrate that myocardial adaptation to ischemia induced by …

Background—Left ventricular hypertrophy (LVH) represents both an adaptive response to
increased cardiac work load and a precursor state of heart failure. Recent evidence linked …

Significant numbers of myocytes die by apoptosis during myocardial infarction. The
molecular mechanism of this process, however, remains largely unexplored. To facilitate a …

Myocardial infarction was produced in rats and the contribution of apoptotic and necrotic
myocyte cell death was measured quantitatively. Myocyte cell death by apoptosis involved …

To determine the effects of aging on myocyte cell death, Fischer 344 rats at 3, 7, 12, 16, and
24 mo of age were injected with myosin monoclonal antibody for the localization and …