I. INTRODUCTION Although about 30 years ago Siekievitz (1959) already speculated about
the possible role of reversible binding of" soluble" enzymes to cellular membranes in …

MATERIALS AND METHODS All experiments were performed on washed mitochondrial
fractions from rat liver, corresponding essentially to the sum of fractions M and L of de Duve …

Results The wet weight to dry weight ratios obtained for kidney tissue from normal and from
adrenalectomized rats under the sampling conditions described above did not differ …

The other papers of this series (l-5)'present experimental evidence for possible relationships
between the kinetics of oxygen, glucose, adenosine diphosphate, adenosine triphosphate …

A survey of the existing data on the interactions of glycolytic enzymes with the cellular
structure in mammalian tissues has substantiated the occurrence of an extensive degree of …

The inhibition of glycolysis by respiration (Pasteur effect) and the inhibition of respiration by
glycolysis (Crabtree effect) represent nonhormonal regulatory mechanisms of cellular …

Horecker (1) has demonstrated the occurrence of a cyclic mechanism in yeast and animal
tissues which can account for the oxidation of carbohydrate to carbon dioxide and water …

Experiment's on aerobic and anaerobic glycolysis in mammalian tissues have usually been
conducted either with slices or with extracts. The latter have usually been made by breaking …

RESULTS Enzyme Act&&es-In terms of maximal velocities (Table II), on the main pathway
the least active enzyme per unit of tissue weight is aldolase, with hexokinase and P …

Recognition of addit, ional pathways of glucose dissimilation via pentose (l-3) has led to
considerable interest in the extent to which the pentose route participates in the metabolism …