Background Numerous studies have reported the correlation between AXIN2 polymorphism
and cancer risk, but the results seem not consistent. In order to get an overall, accurate and …

Background Variants in the axis inhibition 2 (AXIN2) gene might alter the protein's structure
or function or create a multiprotein destruction complex in the Wnt signaling pathway and …

Background Many epidemiological studies have investigated association of AXIN2 variants
on overall cancer risks; however, the available results remain inconsistent. Methods An …

Plenty of epidemiological studies have assessed the effects of AXIN2 polymorphisms on the
risk of developing cancer, but the available results were somewhat inconclusive. Odds ratios …

Previous meta-analyses reported that the variant T allele of Axin2 rs2240308 is associated
with a decreased cancer risk. However, more recent findings have been inconsistent …

Several studies have reported an association between− 148 C/T polymorphism of Axis
inhibition protein 2 (Axin2) and cancer risk; however, the results are inconsistent. In this …

Axin2 is involved in the regulation of Wnt/β-catenin pathway and implicated in cancer
development and progression. The association between AXIN2 rs2240308 polymorphism …

Background: The association of genetic polymorphisms at Axis inhibition protein 2 (AXIN2)
gene and susceptibility to different cancer has attracted much interest. The present study …

Accumulated evidence suggests that alterations due to mutations or genetic polymorphisms
in the AXIN2 tumor suppressor gene, a component of the Wnt signaling pathway, contributes …

Abstract Axis inhibition protein 2 (Axin2) is a negative regulator of the canonical Wnt/β-
catenin signaling pathway, and functions as a tumor suppressor in a number of human …