Idiopathic pulmonary fibrosis in the United States: time to diagnosis and treatment

MB Herberts, TT Teague, V Thao… - BMC Pulmonary …, 2023 - Springer
Objective Create a timeline of diagnosis and treatment for IPF in the US. Design, setting, and
participants A retrospective analysis was performed in collaboration with the OptumLabs …

Patient considerations and drug selection in the treatment of idiopathic pulmonary fibrosis

MA Trawinska, RD Rupesinghe… - Therapeutics and Clinical …, 2016 - Taylor & Francis
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease of unknown
cause. Approximately 5,000 people are diagnosed with IPF in the UK every year. People …

Idiopathic pulmonary fibrosis: clinically meaningful primary endpoints in phase 3 clinical trials

G Raghu, HR Collard, KJ Anstrom… - American journal of …, 2012 - atsjournals.org
Definitive evidence of clinical efficacy in a Phase 3 trial is best shown by a beneficial impact
on a clinically meaningful endpoint—that is, an endpoint that directly measures how a …

Idiopathic pulmonary fibrosis: treatment options in pursuit of evidence-based approaches

G Raghu - European Respiratory Journal, 2006 - Eur Respiratory Soc
The long-standing need to determine an effective medical treatment regimen with clinically
significant and relevant end-points to improve outcome for patients with idiopathic …

Clinical deterioration in patients with idiopathic pulmonary fibrosis: causes and assessment

RJ Panos, RL Mortenson, SA Niccoli… - The American journal of …, 1990 - Elsevier
Patients with idiopathic pulmonary fibrosis (IPF) inevitably experience declines in functional
status that are most frequently due to progressive pulmonary fibrosis. However, the cause of …

Severe idiopathic pulmonary fibrosis: A clinical approach

R Lipsi, D Mazzola, A Caminati, D Elia, C Lonati… - European Journal of …, 2018 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a devastating progressive disease associated with a
high mortality rate. Novel antifibrotic therapies have been recently demonstrated to slow …

Impact of reduction in antifibrotic treatment on mortality in idiopathic pulmonary fibrosis

S Porse, N Hoyer, SB Shaker - Respiratory medicine, 2022 - Elsevier
Introduction Idiopathic pulmonary fibrosis (IPF) is a severe interstitial lung disease for which
two effective antifibrotics, nintedanib and pirfenidone, are available. However, many patients …

Incidence, prevalence, and survival of patients with idiopathic pulmonary fibrosis in the UK

H Strongman, I Kausar, TM Maher - Advances in therapy, 2018 - Springer
Introduction Recent developments in the care of patients with idiopathic pulmonary fibrosis
have the potential to improve survival rates. Population-based estimates of the current …

[HTML][HTML] Idiopathic pulmonary fibrosis in the era of antifibrotic therapy: Searching for new opportunities grounded in evidence

C Robalo-Cordeiro, P Campos, L Carvalho… - Revista Portuguesa de …, 2017 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease that up to now has
been associated with a poor prognosis. However, the results of the INPULSIS and ASCEND …

Predictors of mortality poorly predict common measures of disease progression in idiopathic pulmonary fibrosis

B Ley, WZ Bradford, E Vittinghoff… - American journal of …, 2016 - atsjournals.org
Rationale: Mortality prediction is well studied in idiopathic pulmonary fibrosis (IPF), but little
is known about predictors of premortality disease progression. Identification of patients at …