End of an ERA: lessons from negative clinical trials in idiopathic pulmonary fibrosis

PW Noble, L Richeldi, N Kaminski - American journal of respiratory …, 2011 - atsjournals.org
The article by King and coworkers in this issue of the Journal (pp. 92–99) reports the results
of BUILD-3, a large, randomized, and placebo-controlled trial that evaluated the efficacy of …

[HTML][HTML] Clinical features, diagnosis, management, and outcomes of idiopathic pulmonary fibrosis in Korea: analysis of the Korea IPF Cohort (KICO) registry

Y Jegal, JS Park, SY Kim, H Yoo… - Tuberculosis and …, 2022 - ncbi.nlm.nih.gov
Background The Korea Interstitial Lung Disease Study Group has made a new nationwide
idiopathic pulmonary fibrosis (IPF) registry because the routine clinical practice has changed …

[HTML][HTML] Clinico-radiological features and efficacy of anti-fibrotic agents in atypical idiopathic pulmonary fibrosis

K Sugino, H Shimizu, Y Nakamura… - Journal of Thoracic …, 2018 - ncbi.nlm.nih.gov
Background Atypical idiopathic pulmonary fibrosis (IPF) including multiple cysts or markedly
atelectatic induration in upper lung predominance occasionally can confirm the diagnosis of …

Delay and inequalities in the treatment of idiopathic pulmonary fibrosis: the case of two Nordic countries

I Pesonen, L Carlson, N Murgia, R Kaarteenaho… - Multidisciplinary …, 2018 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is characterized by progressive loss of lung
function with high mortality within the first 5 years from diagnosis. In 2011–2014, two drugs …

Outcomes after hospitalization in idiopathic pulmonary fibrosis: a cohort study

AW Brown, CP Fischer, OA Shlobin, RG Buhr, S Ahmad… - Chest, 2015 - Elsevier
OBJECTIVE The outcomes of patients with idiopathic pulmonary fibrosis (IPF) who undergo
hospitalization have not been well characterized. We sought to determine the frequency of …

Cost-effectiveness of the anti-fibrotics for the treatment of idiopathic pulmonary fibrosis in the United States

TM Dempsey, V Thao, JP Moriarty, BJ Borah… - BMC Pulmonary …, 2022 - Springer
Background The anti-fibrotic medications nintedanib and pirfenidone were approved in the
United States for use in patients with idiopathic pulmonary fibrosis several years ago. While …

Assessing the effectiveness of pirfenidone in idiopathic pulmonary fibrosis: long-term, real-world data from European IPF Registry (eurIPFreg)

E Krauss, S Tello, J Wilhelm, J Schmidt… - Journal of clinical …, 2020 - mdpi.com
Background: Idiopathic pulmonary fibrosis (IPF) is a chronic progressive fibrotic pulmonary
disease with rising incidence. In this study the effectiveness of pirfenidone, as measured by …

Idiopathic pulmonary fibrosis: outcome in relation to smoking status

KM Antoniou, DM Hansell, MB Rubens… - American journal of …, 2008 - atsjournals.org
Rationale: The pathogenic importance of smoking status in idiopathic pulmonary fibrosis
(IPF) is uncertain. In theory, increased oxidative stress in current and former smokers might …

Challenges in idiopathic pulmonary fibrosis trials: the point on end-points

C Albera - European Respiratory Review, 2011 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF) is the most common of the idiopathic interstitial
pneumonias and is associated with both a variable clinical course and a poor prognosis …

Real-world cohort evaluation of the impact of the antifibrotics in patients with idiopathic pulmonary fibrosis

TM Dempsey, V Thao, DA Helfinstine… - European …, 2023 - Eur Respiratory Soc
Extract The antifibrotic medications pirfenidone and nintedanib became the first US Food
and Drug Administration (FDA)-approved medical therapy for the treatment of idiopathic …