Progression of frailty in survivors of childhood cancer: a St. Jude lifetime cohort report
Background Some adult survivors of childhood cancers develop frailty at higher rates than
expected based on their chronological age. This study examined the incidence of frailty …
expected based on their chronological age. This study examined the incidence of frailty …
Physiologic frailty as a sign of accelerated aging among adult survivors of childhood cancer: a report from the St Jude Lifetime cohort study
Purpose Frailty, a phenotype reported among 9.9% of individuals 65 years old and older
(9.6% of women; 5.2% of men), has not been assessed among adult childhood cancer …
(9.6% of women; 5.2% of men), has not been assessed among adult childhood cancer …
Prevalence and predictors of frailty in childhood cancer survivors and siblings: a report from the childhood cancer survivor study
S Hayek, TM Gibson, WM Leisenring… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE To estimate the prevalence of frailty among childhood cancer survivors and to
determine the direct and indirect effects of treatment exposures, lifestyle factors, and severe …
determine the direct and indirect effects of treatment exposures, lifestyle factors, and severe …
Frailty and quality of life in adult survivors of childhood cancer
Introduction: Adult survivors of childhood cancer are at risk for frailty, a state of diminished
physiologic reserve, typically seen in older adults, associated with morbidity and mortality …
physiologic reserve, typically seen in older adults, associated with morbidity and mortality …
Premature physiologic aging as a paradigm for understanding increased risk of adverse health across the lifespan of survivors of childhood cancer
KK Ness, JL Kirkland, MM Gramatges… - Journal of Clinical …, 2018 - ascopubs.org
The improvement in survival of childhood cancer observed across the past 50 years has
resulted in a growing acknowledgment that simply extending the lifespan of survivors is not …
resulted in a growing acknowledgment that simply extending the lifespan of survivors is not …
Physiologic frailty and neurocognitive decline among young-adult childhood cancer survivors: a prospective study from the St Jude Lifetime Cohort
PURPOSE Eight percent of young-adult childhood cancer survivors meet criteria for frailty,
an aging phenotype associated with poor health. In the elderly general population, frailty is …
an aging phenotype associated with poor health. In the elderly general population, frailty is …
Accelerated aging among cancer survivors: from pediatrics to geriatrics
TO Henderson, KK Ness, HJ Cohen - American Society of Clinical …, 2014 - ascopubs.org
There are almost 14-million cancer survivors in the United States and the population is
growing. Almost two-thirds of these survivors are age 65 or older. Given this, it is imperative …
growing. Almost two-thirds of these survivors are age 65 or older. Given this, it is imperative …
Frailty and comorbidities among survivors of adolescent and young adult cancer: a cross-sectional examination of a hospital-based survivorship cohort
Purpose: Cancer survivors are at increased risk for the early development of age-related
chronic medical conditions compared with peers without a history of cancer; however, little is …
chronic medical conditions compared with peers without a history of cancer; however, little is …
Frailty in childhood cancer survivors
Young adult childhood cancer survivors are at an increased risk of frailty, a physiologic
phenotype typically found among older adults. This phenotype is associated with new‐onset …
phenotype typically found among older adults. This phenotype is associated with new‐onset …
Frailty and risk of mortality in older cancer survivors and adults without a cancer history: Evidence from the National Health and Nutrition Examination Survey, 1999 …
BACKGROUND Epidemiologic evidence reporting the role of frailty in survival among older
adults with a prior cancer diagnosis is limited. METHODS A total of 2050 older adults (≥ 60 …
adults with a prior cancer diagnosis is limited. METHODS A total of 2050 older adults (≥ 60 …
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