[HTML][HTML] Broadening horizons in mechanisms, management, and treatment of diabetic kidney disease

A Petrazzuolo, G Sabiu, E Assi, A Maestroni… - Pharmacological …, 2023 - Elsevier
Diabetic kidney disease (DKD) is the first cause of end-stage kidney disease in patients with
diabetes and its prevalence is increasing worldwide. It encompasses histological alterations …

Targeting the pathobiology of diabetic kidney disease

MC Thomas - Advances in Chronic Kidney Disease, 2021 - Elsevier
The pathobiology of diabetic kidney disease (DKD) involves an interplay between all the
many different cell types that exist within the kidney and their shared and cumulative …

Diabetic nephropathy: novel molecular mechanisms and therapeutic targets

C Zoja, C Xinaris, D Macconi - Frontiers in pharmacology, 2020 - frontiersin.org
Diabetic nephropathy (DN) is one of the major microvascular complications of diabetes
mellitus and the leading cause of end-stage kidney disease. The standard treatments for …

Molecular pathways that drive diabetic kidney disease

S Mohandes, T Doke, H Hu, D Mukhi… - The Journal of …, 2023 - Am Soc Clin Investig
Kidney disease is a major driver of mortality among patients with diabetes and diabetic
kidney disease (DKD) is responsible for close to half of all chronic kidney disease cases …

What's new in the molecular mechanisms of diabetic kidney disease: recent advances

K Watanabe, E Sato, E Mishima, M Miyazaki… - International journal of …, 2022 - mdpi.com
Diabetic kidney disease (DKD) is the leading cause of chronic kidney disease, including end-
stage kidney disease, and increases the risk of cardiovascular mortality. Although the …

Pathophysiologic mechanisms in diabetic kidney disease: A focus on current and future therapeutic targets

J Barrera‐Chimal, F Jaisser - Diabetes, Obesity and …, 2020 - Wiley Online Library
Diabetic kidney disease (DKD) is the primary cause of chronic kidney disease around the
globe and is one of the main complications in patients with type 1 and 2 diabetes. The …

Key pathways in renal disease progression of experimental diabetes

C Zoja, C Zanchi, A Benigni - Nephrology Dialysis …, 2015 - academic.oup.com
Diabetic nephropathy (DN) is one of the major microvascular complications of diabetes
mellitus and the leading cause of end-stage kidney disease. Both diabetes and chronic …

Recent advances in the emerging therapeutic strategies for diabetic kidney diseases

W Huang, YY Chen, ZQ Li, FF He, C Zhang - International Journal of …, 2022 - mdpi.com
Diabetic kidney disease (DKD) is one of the most common causes of end-stage renal
disease worldwide. The treatment of DKD is strongly associated with clinical outcomes in …

Tubular injury in diabetic kidney disease: molecular mechanisms and potential therapeutic perspectives

Y Wang, M Jin, CK Cheng, Q Li - Frontiers in Endocrinology, 2023 - frontiersin.org
Diabetic kidney disease (DKD) is a chronic complication of diabetes and the leading cause
of end-stage renal disease (ESRD) worldwide. Currently, there are limited therapeutic drugs …

Present and future directions in diabetic kidney disease

CP Limonte, M Kretzler, S Pennathur… - Journal of Diabetes and …, 2022 - Elsevier
Diabetic kidney disease (DKD) is the leading cause of kidney failure and is associated with
substantial risk of cardiovascular disease, morbidity, and mortality. Traditionally, DKD …