Diabetic nephropathy is the commonest cause of end-stage renal disease in most
developed economies. Current standard of care for diabetic nephropathy embraces …

Diabetic kidney disease (DKD) is a chronic complication of diabetes mellitus which may
eventually lead to end‐stage kidney disease (ESKD). Despite improvements in glycaemic …

Introduction: At present, treatment of diabetic kidney disease (DKD) is still mainly based on
drugs acting on glycemic and blood pressure control, as there is no validated therapy able to …

Type 1 diabetes mellitus is an autoimmune disease characterized by progressive
destruction of pancreatic beta cells by genetic and environmental factors which leads to an …

The db/db mouse is the most widely used animal model of type 2 diabetic nephropathy.
Recent studies have utilized genetic backcrossing with transgenic mouse strains to create …

The increasing global prevalence of type 2 diabetes mellitus (T2DM) and chronic kidney
disease (CKD) has prompted research efforts to tackle the growing epidemic of diabetic …

Diabetic kidney disease develops in approximately 40% of patients who are diabetic and is
the leading cause of CKD worldwide. Although ESRD may be the most recognizable …

Diabetic kidney disease (DKD) is one of the major causes of morbidity and mortality in
diabetic patients and also the leading single cause of end-stage renal disease in the United …

A critical challenge faced by clinical nephrologists today is the escalating number of patients
developing end stage renal disease, a major proportion of which is attributed to diabetic …

Diabetic nephropathy is characterized by excessive amassing of extracellular matrix (ECM)
with thickening of glomerular and tubular basement membranes and increased amount of …