Acute pancreatitis: animal models and recent advances in basic research

YC Chan, PS Leung - Pancreas, 2007 - journals.lww.com
Acute pancreatitis (AP) is characterized by edema, acinar cell necrosis, hemorrhage, and
severe inflammation of the pancreas. Patients with AP present with elevated blood and urine …

The clinical course of acute pancreatitis and the inflammatory mediators that drive it

L Kylänpää, Z Rakonczay Jr… - International journal of …, 2012 - Wiley Online Library
Acute pancreatitis (AP) is a common emergency condition. In the majority of cases, it
presents in a mild and self‐limited form. However, about 20% of patients develop severe …

Pathogenic mechanisms of acute pancreatitis

RP Sah, P Garg, AK Saluja - Current opinion in gastroenterology, 2012 - journals.lww.com
New findings necessitate a paradigm shift in our understanding of acute pancreatitis. Intra-
acinar trypsinogen activation leads to early pancreatic injury, but the inflammatory response …

Pathophysiology of acute pancreatitis

M Bhatia, FL Wong, Y Cao, HY Lau, J Huang, P Puneet… - Pancreatology, 2005 - karger.com
Acute pancreatitis is a common clinical condition. It is a disease of variable severity in which
some patients experience mild, self-limited attacks while others manifest a severe, highly …

Acute pancreatitis: a literature review.

RK Jha, Q Ma, H Sha, M Palikhe - Medical science monitor …, 2009 - europepmc.org
Acute pancreatitis (AP) is an inflammatory disease characterized by steady, acute
abdominal pain of varying severity, often radiating from the epigastrium to the back. Its …

[HTML][HTML] Murine models of acute pancreatitis: a critical appraisal of clinical relevance

P Silva-Vaz, AM Abrantes, M Castelo-Branco… - International journal of …, 2019 - mdpi.com
Acute pancreatitis (AP) is a severe disease associated with high morbidity and mortality.
Clinical studies can provide some data concerning the etiology, pathophysiology, and …

Acute pancreatitis: bench to the bedside

SJ Pandol, AK Saluja, CW Imrie, PA Banks - Gastroenterology, 2007 - gastrojournal.org
Acute pancreatitis is an acute inflammatory process of the pancreas that frequently involves
peripancreatic tissues and at times remote organ systems. The severity of the disease varies …

[HTML][HTML] Update on pathogenesis and clinical management of acute pancreatitis

DM Cruz-Santamaría, C Taxonera… - World journal of …, 2012 - ncbi.nlm.nih.gov
Acute pancreatitis (AP), defined as the acute nonbacterial inflammatory condition of the
pancreas, is derived from the early activation of digestive enzymes found inside the acinar …

Etiopathogenesis of acute pancreatitis

S Karne, FS Gorelick - Surgical Clinics of North America, 1999 - Elsevier
Acute pancreatitis (AP) is a disease characterized by abdominal pain and elevations in the
serum levels of amylase and lipase. 27 A key feature of AP is the elaboration of an …

Etiology and pathogenesis of acute pancreatitis: current concepts

GH Sakorafas, AG Tsiotou - Journal of clinical gastroenterology, 2000 - journals.lww.com
Acute pancreatitis is a disorder that has numerous causes and an obscure pathogenesis.
Bile duct stones and alcohol abuse together account for about 80% of acute pancreatitis …