New approaches to acute pancreatitis: role of inflammatory mediators
JG Norman - Digestion, 1999 - karger.com
Regardless of whether the initiating event is alcohol, gallstones or some other less common
cause, acute pancreatitis progresses in a predictable manner eventually leading to failure of …
cause, acute pancreatitis progresses in a predictable manner eventually leading to failure of …
Pathophysiology of pancreatitis Role of cytokines and other mediators of inflammation
AK Saluja, ML Steer - Digestion, 1999 - karger.com
Acute pancreatitis is an inflammatory disease, which varies in severity from mild to severe.
Factors determining the severity of pancreatitis are not known. It is generally believed that …
Factors determining the severity of pancreatitis are not known. It is generally believed that …
Pathophysiological mechanisms of acute pancreatitis define inflammatory markers of clinical prognosis
GA Minkov, KS Halacheva, YP Yovtchev… - Pancreas, 2015 - journals.lww.com
Abstract Development of acute pancreatitis illustrates the need to understand the basic
mechanisms of disease progression to drive the exploration of therapeutic options …
mechanisms of disease progression to drive the exploration of therapeutic options …
[HTML][HTML] Inflammation and immunosuppression in severe acute pancreatitis
ML Kylänpää, H Repo… - World journal of …, 2010 - ncbi.nlm.nih.gov
Acute pancreatitis (AP) is a common disease, which usually exists in its mild form. However,
in a fifth of cases, the disease is severe, with local pancreatic complications or systemic …
in a fifth of cases, the disease is severe, with local pancreatic complications or systemic …
Pathophysiology of acute experimental pancreatitis: lessons from genetically engineered animal models and new molecular approaches
C Schäfer, AB Tietz, B Göke - Digestion, 2005 - karger.com
The incidence of acute pancreatitis is growing and worldwide population-based studies
report a doubling or tripling since the 1970s. 25% of acute pancreatitis are severe and …
report a doubling or tripling since the 1970s. 25% of acute pancreatitis are severe and …
Practical guide to the management of acute pancreatitis
G Goodchild, M Chouhan, GJ Johnson - Frontline Gastroenterology, 2019 - fg.bmj.com
Acute pancreatitis (AP) is characterised by inflammation of the exocrine pancreas and is
associated with acinar cell injury and both a local and systemic inflammatory response. AP …
associated with acinar cell injury and both a local and systemic inflammatory response. AP …
Acute pancreatitis: a multifaceted set of organelle and cellular interactions
Acute pancreatitis is an inflammatory disorder of the exocrine pancreas associated with
tissue injury and necrosis. The disease can be mild, involving only the pancreas, and …
tissue injury and necrosis. The disease can be mild, involving only the pancreas, and …
Apoptosis versus necrosis in acute pancreatitis
M Bhatia - … Journal of Physiology-Gastrointestinal and Liver …, 2004 - journals.physiology.org
Acute pancreatitis is a disease of variable severity in which some patients experience mild,
self-limited attacks, whereas others manifest a severe, highly morbid, and frequently lethal …
self-limited attacks, whereas others manifest a severe, highly morbid, and frequently lethal …
Early events in acute pancreatitis
ML Steer - Best Practice & Research Clinical Gastroenterology, 1999 - Elsevier
Studies using experimental models indicate that the earliest changes in acute pancreatitis
involve intra-acinar cell events including the co-localization of lysosomal hydrolases with …
involve intra-acinar cell events including the co-localization of lysosomal hydrolases with …
Current management of acute pancreatitis
The incidence of acute pancreatitis varies considerably between regions and is estimated at
5–80 per 100,000 population. The mortality rate of acute edematous-interstitial pancreatitis …
5–80 per 100,000 population. The mortality rate of acute edematous-interstitial pancreatitis …