Dietary phenolics against colorectal cancer—From promising preclinical results to poor translation into clinical trials: Pitfalls and future needs

MA Núñez‐Sánchez… - Molecular nutrition & …, 2015 - Wiley Online Library
Colorectal cancer (CRC) remains a major cause of cancer death worldwide. Over 70% of
CRC cases are sporadic and related to lifestyle. Epidemiological studies inversely correlate …

Medicinal plants in the prevention and treatment of colon cancer

P Aiello, M Sharghi, SM Mansourkhani… - Oxidative Medicine …, 2019 - Wiley Online Library
The standard treatment for cancer is generally based on using cytotoxic drugs, radiotherapy,
chemotherapy, and surgery. However, the use of traditional treatments has received …

Pomegranate extracts and cancer prevention: molecular and cellular activities

DN Syed, JC Chamcheu, VM Adhami… - Anti-Cancer Agents in …, 2013 - ingentaconnect.com
There is increased appreciation by the scientific community that dietary phytochemicals can
be potential weapons in the fight against cancer. Emerging data has provided new insights …

Chemopreventive effect of dietary polyphenols in colorectal cancer cell lines

JR Araújo, P Gonçalves, F Martel - Nutrition research, 2011 - Elsevier
Colorectal cancer (CRC) is the second most fatal and the third most diagnosed type of
cancer worldwide. Despite having multifactorial causes, most CRC cases are mainly …

[HTML][HTML] Research progress on chemopreventive effects of phytochemicals on colorectal cancer and their mechanisms

TF Yin, M Wang, Y Qing, YM Lin… - World journal of …, 2016 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is a type of cancer with high morbidity and mortality rates
worldwide and has become a global health problem. The conventional radiotherapy and …

[PDF][PDF] The role of pomegranate (Punica granatum L.) in colon cancer.

SA Khan - Pakistan journal of pharmaceutical sciences, 2009 - emro.who.int
Colon cancer is one of the major causes of cancer-related death in the Western world.
Although cytotoxic chemotherapeutic agents are available to treat the disease, these agents …

Case–control study on beneficial effect of regular consumption of apples on colorectal cancer risk in a population with relatively low intake of fruits and vegetables

W Jedrychowski, U Maugeri, T Popiela… - European Journal of …, 2010 - journals.lww.com
Laboratory in-vitro studies and animal experiments showing the potential health benefits
from apples raises the question to what extent the regular consumption of apples in humans …

Cancer chemoprevention by pomegranate: laboratory and clinical evidence

VM Adhami, N Khan, H Mukhtar - Nutrition and cancer, 2009 - Taylor & Francis
Pomegranate fruit from the tree Punica granatum has been dubbed as the “nature's power
fruit.” Dating back to Biblical times, the tree itself is attributed to possess extraordinary …

Chemoprevention of colorectal cancer by grape seed proanthocyanidin is accompanied by a decrease in proliferation and increase in apoptosis

H Nomoto, M Iigo, H Hamada, S Kojima… - Nutrition and …, 2004 - Taylor & Francis
Effects of proanthocyanidin (PA), procyanidin B-2 (B-2), and epigallocatechin gallate
(EGCG) on azoxymethane (AOM)-induced colonic preneoplastic aberrant crypt foci (ACF) …

The protective effect of polyphenols for colorectal cancer

S Ding, S Xu, J Fang, H Jiang - Frontiers in immunology, 2020 - frontiersin.org
Colorectal cancer (CRC) is one of the most prevalent cancers that threaten people in many
countries. It is a multi-factorial chronic disease caused by a combination of genetic and …