After congenital heart defects neural tube defects (NTDs) is the second most prevalent
congenital malformation among birth defects. The average rate of isolated NTDs is 1.4-2.0 …

Neural tube defects (NTDs), a set of structural abnormalities affecting the brain, spinal cord,
and the skeletal and connective tissues that protect them, are common malformations …

The number of mouse mutants and strains with neural tube defects (NTDs) now exceeds
240, including 205 representing specific genes, 30 for unidentified genes, and 9 …

Background Neural tube defects (NTD) are among the most common defects affecting 1:
1000 births. They are caused by a failure of neural tube closure during development. Their …

The molecular requirements for neural tube closure are complex. This is illustrated by the
occurrence of neural tube defects (NTDs) in many genetic mouse mutants, which implicate a …

BACKGROUND Neural tube closure is a critical embryological process that requires the
coordination of many molecular and cellular events. Only recently has the molecular basis of …

Purpose Neural tube defects are a group of birth defects caused by failure of neural tube
closure during development. The etiology of NTD, requiring a complex interaction between …

The epidemiological investigation of the common open neural tube defects (NTDs),
anencephaly, and spina bifida, has a long history. The most significant finding from these …

Spina bifida, anencephaly, and encephalocele are commonly grouped together and termed
neural tube defects (NTD). Failure of closure of the neural tube during development results …

Background Neural tube defects (NTDs) are debilitating birth defects involving the central
nervous system (CNS). Despite recent advances, NTDs represent the second most common …