[HTML][HTML] Asian Zika virus isolate significantly changes the transcriptional profile and alternative RNA splicing events in a neuroblastoma cell line

G Bonenfant, R Meng, C Shotwell, P Badu, AF Payne… - Viruses, 2020 - mdpi.com
The alternative splicing of pre-mRNAs expands a single genetic blueprint to encode
multiple, functionally diverse protein isoforms. Viruses have previously been shown to …

[HTML][HTML] ZIKV infection effects changes in gene splicing, isoform composition and lncRNA expression in human neural progenitor cells

B Hu, Y Huo, L Yang, G Chen, M Luo, J Yang, J Zhou - Virology journal, 2017 - Springer
Abstract Background The Zika virus (ZIKV) is a mosquito-borne flavivirus that causes
microcephaly and Guillain-Barré syndrome in infected individuals. To obtain insights into the …

[HTML][HTML] Zika virus infection differentially affects genome-wide transcription in neuronal cells and myeloid dendritic cells

T Park, M Kang, S Baek, CH Lee, D Park - PLoS One, 2020 - journals.plos.org
Zika virus (ZIKV) is an emerging mosquito-borne flavivirus that has attracted global attention
and international awareness. ZIKV infection exhibits mild symptoms including fever and …

In silico analysis revealed Zika virus miRNAs associated with viral pathogenesis through alteration of host genes involved in immune response and neurological …

MS Islam, MAAK Khan, MW Murad… - Journal of medical …, 2019 - Wiley Online Library
Abstract Background The concurrent Zika Virus (ZIKV) outbreaks in the United States and
Northeast Brazil have evoked global surveillance. Zika infection has been correlated with …

[HTML][HTML] Tissue-specific expansion of Zika virus isogenic variants drive disease pathogenesis

KWK Chan, AM Bifani, S Watanabe, MM Choy… - …, 2023 - thelancet.com
Summary Background The Asian lineage Zika virus (ZIKV) emerged as a public health
emergency in 2016 causing severe neurological pathologies with no apparent historical …

Characterization of cis-Acting RNA Elements of Zika Virus by Using a Self-Splicing Ribozyme-Dependent Infectious Clone

ZY Liu, JY Yu, XY Huang, H Fan, XF Li… - Journal of …, 2017 - Am Soc Microbiol
Zika virus (ZIKV) has caused significant outbreaks and epidemics in the Americas recently,
raising global concern due to its ability to cause microcephaly and other neurological …

[HTML][HTML] MicroRNA and mRNA dysregulation in astrocytes infected with Zika virus

RA Kozak, A Majer, MJ Biondi, SJ Medina, LW Goneau… - Viruses, 2017 - mdpi.com
The Zika virus (ZIKV) epidemic is an ongoing public health concern. ZIKV is a flavivirus
reported to be associated with microcephaly, and recent work in animal models …

[HTML][HTML] The impact of Zika virus infection on human neuroblastoma (SH-SY5Y) cell line

N Luplertlop, S Suwanmanee… - Journal of vector …, 2017 - journals.lww.com
Methods: ZIKV growth kinetics, viral toxicity, and SH-SY5Y cell vialibity were determined
after ZIKV infection in SH-SY5Y cells in vitro. ZIKV-infected SH-SY5Y cells were …

[HTML][HTML] A single amino acid substitution in the capsid protein of Zika virus contributes to a neurovirulent phenotype

GY Song, XY Huang, MJ He, HY Zhou, RT Li… - Nature …, 2023 - nature.com
Increasing evidence shows the African lineage Zika virus (ZIKV) displays a more severe
neurovirulence compared to the Asian ZIKV. However, viral determinants and the underlying …

Zika virus genome biology and molecular pathogenesis

A Wang, S Thurmond, L Islas, K Hui… - Emerging microbes & …, 2017 - Taylor & Francis
Zika virus (ZIKV) is an emerging RNA virus in the widespread Flavivirus genus. Recently,
ZIKV has rapidly spread around the world and has been implicated in human disease …