PIWI (P element-induced wimpy testis in Drosophila) family proteins are evolutionarily
conserved and have an essential role in male fertility in most of the animal species studied …

P-Element-induced wimpy testis (Piwi) subfamily proteins form complexes that bind to Piwi-
interacting RNA. This interaction is crucial for stem cell regulation and formation …

Piwi proteins play an important regulatory role in germ cell division during gametogenesis
and gonad development. In order to understand the function of Piwi genes in the …

Piwil2, a member of the Argonaute family, is involved in the biogenesis of PIWI-interacting
RNAs (piRNAs) and plays an important role in regulating gametogenesis. In the present …

The P‐element‐induced wimpy testis (PIWI) protein, which associates with small non‐
coding RNAs, is responsible for maintaining the integrity of germ cells and stem cells. Thus …

Increasing piRNAs provide RNA-interference pathways to regulate transposons and gene
expression in germline cells. We demonstrate that Piwi transcripts are exclusively expressed …

Piwi controls the number of primordial germ cells (PGCs) via protecting maternal mRNA from
decay and adult germ stem cell division in Drosophila. In mouse and zebrafish, piwi controls …

Genetic introgression of farmed salmon into wild populations can damage the genetic
integrity of wild stocks and is therefore considered as an environmental threat. One possible …

DNA methylation is an important way to regulate gene expression in eukaryotes. In order to
reveal the role of DNA methylation in the regulation of germ cell-specific piwi gene …

The piwi family genes are crucial for stem cell self-renewal, RNA silencing, and translational
regulation in diverse organisms. However, their function in mammals remains unexplored …