Inappropriate empirical antibiotic treatment in high-risk neutropenic patients with bacteremia in the era of multidrug resistance
G Martinez-Nadal, P Puerta-Alcalde… - Clinical Infectious …, 2020 - academic.oup.com
Background We aimed to describe the current rates of inappropriate empirical antibiotic
treatment (IEAT) in oncohematological patients with febrile neutropenia (FN) and its impact …
treatment (IEAT) in oncohematological patients with febrile neutropenia (FN) and its impact …
Safety and efficacy of antibiotic de-escalation and discontinuation in high-risk hematological patients with febrile neutropenia: a single-center experience
A Verlinden, H Jansens, H Goossens… - Open forum …, 2022 - academic.oup.com
Background There is currently no consensus on optimal duration of antibiotic treatment in
febrile neutropenia. We report on the clinical impact of implementation of antibiotic de …
febrile neutropenia. We report on the clinical impact of implementation of antibiotic de …
[HTML][HTML] Current time-to-positivity of blood cultures in febrile neutropenia: a tool to be used in stewardship de-escalation strategies
P Puerta-Alcalde, C Cardozo, M Suárez-Lledó… - Clinical microbiology …, 2019 - Elsevier
Objectives We aimed to describe the current time-to-positivity (TTP) of blood cultures in
individuals with onco-haematological diseases with febrile neutropenia. We assessed the …
individuals with onco-haematological diseases with febrile neutropenia. We assessed the …
Association between adherence to an antimicrobial stewardship program and mortality among hospitalised cancer patients with febrile neutropaenia: a prospective …
RG Rosa, LZ Goldani, RP dos Santos - BMC infectious diseases, 2014 - Springer
Background Initial management of chemotherapy-induced febrile neutropaenia (FN)
comprises empirical therapy with a broad-spectrum antimicrobial. Currently, there is …
comprises empirical therapy with a broad-spectrum antimicrobial. Currently, there is …
[HTML][HTML] European guidelines for empirical antibacterial therapy for febrile neutropenic patients in the era of growing resistance: summary of the 2011 4th European …
D Averbuch, C Orasch, C Cordonnier… - …, 2013 - ncbi.nlm.nih.gov
Owing to increasing resistance and the limited arsenal of new antibiotics, especially against
Gram-negative pathogens, carefully designed antibiotic regimens are obligatory for febrile …
Gram-negative pathogens, carefully designed antibiotic regimens are obligatory for febrile …
Optimisation of empirical antimicrobial therapy in patients with haematological malignancies and febrile neutropenia (How Long study): an open-label, randomised …
M Aguilar-Guisado, I Espigado… - The Lancet …, 2017 - thelancet.com
Background Continuation of empirical antimicrobial therapy (EAT) for febrile neutropenia in
patients with haematological malignancies until neutrophil recovery could prolong the …
patients with haematological malignancies until neutrophil recovery could prolong the …
De-escalation and discontinuation strategies in high-risk neutropenic patients: an interrupted time series analyses of antimicrobial consumption and impact on …
G la Martire, C Robin, N Oubaya, R Lepeule… - European Journal of …, 2018 - Springer
Febrile neutropenia (FN) is the main reason for antibiotic prescription in hematology wards
where, on the other hand, antibiotic stewardship (AS) is poorly explored. The objectives of …
where, on the other hand, antibiotic stewardship (AS) is poorly explored. The objectives of …
Risk assessment and treatment of low-risk patients with febrile neutropenia
WV Kern - Clinical infectious diseases, 2006 - academic.oup.com
Progress has been made in the development and validation of rules that attempt ito predict a
low risk (< 10%) of severe infection or clinical complications in patients with cancer, fever …
low risk (< 10%) of severe infection or clinical complications in patients with cancer, fever …
Early discontinuation of empirical antibacterial therapy in febrile neutropenia: the ANTIBIOSTOP study
L Le Clech, JP Talarmin, MA Couturier… - Infectious …, 2018 - Taylor & Francis
Introduction: Immediate empirical antibiotic therapy is mandatory in febrile chemotherapy-
induced neutropenia, but its optimal duration is unclear, especially in patients with fever of …
induced neutropenia, but its optimal duration is unclear, especially in patients with fever of …
Time to antibiotics and outcomes in cancer patients with febrile neutropenia
T Perron, M Emara, S Ahmed - BMC health services research, 2014 - Springer
Background Febrile neutropenia is an oncologic emergency. The timing of antibiotics
administration in patients with febrile neutropenia may result in adverse outcomes. Our study …
administration in patients with febrile neutropenia may result in adverse outcomes. Our study …