As one of the top causes of blindness worldwide, glaucoma leads to diverse optic
neuropathies such as degeneration of retinal ganglion cells (RGCs). It is widely accepted …

Glaucoma, the second leading cause of blindness in the world, is a chronic optic neuropathy
often associated with increased intraocular pressure and characterized by progressive …

Normal tension glaucoma (NTG) is a progressive neurodegenerative disease in glaucoma
families. Typical glaucoma develops because of increased intraocular pressure (IOP) …

Glaucoma is the leading cause of irreversible blindness worldwide and is characterized by
the death of retinal ganglion cells. Reduction of intraocular pressure (IOP) is the only …

Background: Glaucoma is characterized as a neuropathic disease that causes progressive
degeneration of retinal ganglion cells (RGCs) in the retina, resulting in irreversible loss of …

Background Neuroprotective therapy for glaucoma can be defined as treatment of the
recalcitrant disease via direct modification of the molecular mechanism involving retinal …

Background In glaucoma, non-intraocular pressure (IOP)-related risk factors can result in
increased levels of extracellular glutamate, which triggers a cascade of neurodegeneration …

Progressive neurodegeneration of the optic nerve and the loss of retinal ganglion cells is a
hallmark of glaucoma, the leading cause of irreversible blindness worldwide, with primary …

Glaucoma is characterized by axonal degeneration of retinal ganglion cells (RGCs) and
apoptotic death of their cell bodies, and lowering intraocular pressure is associated with an …

Glaucoma is a neurodegenerative disease that affects primarily the retinal ganglion cells
(RGCs). Increased intraocular pressure (IOP) is one of the major risk factors for glaucoma …