Relevance of necroptosis in cancer
N Lalaoui, G Brumatti - Immunology and cell biology, 2017 - Wiley Online Library
Resistance to caspase‐dependent apoptosis is often responsible for treatment failures in
cancer. Finding novel therapeutic strategies that can activate alternative cell death programs …
cancer. Finding novel therapeutic strategies that can activate alternative cell death programs …
Therapeutic exploitation of necroptosis for cancer therapy
S Fulda - Seminars in cell & developmental biology, 2014 - Elsevier
Evasion of programmed cell death represents one of the hallmarks of cancers that
contributes to tumor initiation, progression and treatment resistance. This calls for novel …
contributes to tumor initiation, progression and treatment resistance. This calls for novel …
[HTML][HTML] The role of necroptosis in the treatment of diseases
YS Cho - BMB reports, 2018 - ncbi.nlm.nih.gov
Necroptosis is an emerging form of programmed cell death occurring via active and well-
regulated necrosis, distinct from apoptosis morphologically, and biochemically. Necroptosis …
regulated necrosis, distinct from apoptosis morphologically, and biochemically. Necroptosis …
The role of necroptosis in cancer: A double-edged sword?
X Qin, D Ma, Y Tan, H Wang, Z Cai - … et Biophysica Acta (BBA)-Reviews on …, 2019 - Elsevier
Necroptosis is a programmed, caspase-independent cell death that is morphologically
similar to necrosis. Unlike apoptosis, necroptosis evokes inflammatory responses by …
similar to necrosis. Unlike apoptosis, necroptosis evokes inflammatory responses by …
The mechanism of necroptosis in normal and cancer cells
S Fulda - Cancer biology & therapy, 2013 - Taylor & Francis
Programmed cell death is a basic cellular process that is critical to maintain tissue
homeostasis. Besides apoptosis, necroptosis has more recently been discovered as another …
homeostasis. Besides apoptosis, necroptosis has more recently been discovered as another …
Cancer and necroptosis: friend or foe?
Regulated cell death is one major factor to ensure homoeostasis in multicellular organisms.
For decades, apoptosis was considered as the sole form of regulated cell death, whereas …
For decades, apoptosis was considered as the sole form of regulated cell death, whereas …
Necroptosis: a pathogenic negotiator in human diseases
Over the past few decades, mechanisms of programmed cell death have attracted the
scientific community because they are involved in diverse human diseases. Initially …
scientific community because they are involved in diverse human diseases. Initially …
[HTML][HTML] Targeting necroptosis in anticancer therapy: mechanisms and modulators
Y Wu, G Dong, C Sheng - Acta Pharmaceutica Sinica B, 2020 - Elsevier
Necroptosis, a genetically programmed form of necrotic cell death, serves as an important
pathway in human diseases. As a critical cell-killing mechanism, necroptosis is associated …
pathway in human diseases. As a critical cell-killing mechanism, necroptosis is associated …
Necroptotic cell death in anti‐cancer therapy
Necroptosis is one the best‐characterized forms of regulated necrosis. Necroptosis is
mediated by the kinase activities of receptor interacting protein kinase‐1 and receptor …
mediated by the kinase activities of receptor interacting protein kinase‐1 and receptor …
Necroptosis and tumor progression
Necroptosis, a form of programmed necrotic cell death, is a gatekeeper of host defense
against certain pathogen invasions. The deregulation of necroptosis is also a key factor of …
against certain pathogen invasions. The deregulation of necroptosis is also a key factor of …