Rodent models for human diseases

TF Vandamme - European journal of pharmacology, 2015 - Elsevier
One of the factors limiting the translation of knowledge from preclinical studies to the clinic
has been the limitations of in vivo diseases models. Except in the case of highly controlled …

Of mice and men and larvae: Galleria mellonella to model the early host-pathogen interactions after fungal infection

AM Borman - Virulence, 2018 - Taylor & Francis
Candida species are the most common fungal causes of deep-seated and disseminated
infections in immunocompromised human hosts, and are associated with high morbidity and …

[图书][B] Diagnosis and treatment of human mycoses

DR Hospenthal, MG Rinaldi - 2007 - books.google.com
Diagnosis and Treatment of Human Mycoses brings together globally-recognized mycoses
experts to guide readers in the use of current knowledge in the field of medical mycology to …

Mastomys Species as Model Systems for Infectious Diseases

D Hasche, F Rösl - Viruses, 2019 - mdpi.com
Replacements of animal models by advanced in vitro systems in biomedical research,
despite exceptions, are currently still not satisfactory in reproducing the whole complexity of …

Methods for using Galleria mellonella as a model host to study fungal pathogenesis

BB Fuchs, E O'Brien, JB El Khoury, E Mylonakis - Virulence, 2010 - Taylor & Francis
The facile inoculum delivery and handling of the insect Galleria mellonella make it a
desirable model for the study of fungal pathogenesis. Here we present methods to study …

[图书][B] Clinical Mycology E-Book

EJ Anaissie, MR McGinnis, MA Pfaller - 2009 - books.google.com
The first book of its kind to focus on the diagnosis, prevention, and treatment of patients with
fungal infections, this definitive reference returns in a completely revised, full-color new …

Animal models testing monotherapy versus combination antifungal therapy: lessons learned and future directions

KV Clemons, DA Stevens - Current Opinion in Infectious Diseases, 2006 - journals.lww.com
The data derived from animal model studies of antifungal drug efficacy have proven to be
predictive of clinical utility. Studies on combination therapy will prove useful to the clinician …

Developing animal models for polymicrobial diseases

LO Bakaletz - Nature Reviews Microbiology, 2004 - nature.com
Polymicrobial diseases involve two or more microorganisms that act synergistically, or in
succession, to mediate complex disease processes. Although polymicrobial diseases in …

Fungal vaccines and immunotherapy

E Segal, D Elad - Journal de Mycologie Médicale, 2006 - Elsevier
This article reviews the evolution of the development of vaccines against the major fungal
pathogens, the state of art of these attempts and future prospects for vaccines for human and …

[图书][B] Oxford textbook of medical mycology

CC Kibbler, R Barton, NAR Gow, S Howell… - 2017 - books.google.com
The Oxford Textbook of Medical Mycology is a comprehensive reference text which brings
together the science and medicine of human fungal disease. Written by a leading group of …