Regulation of cardiac remodeling by nitric oxide: focus on cardiac myocyte hypertrophy and apoptosis
KC Wollert, H Drexler - Heart failure reviews, 2002 - Springer
Cardiac hypertrophy occurs in pathological conditions associated with chronic increases in
hemodynamic load. Although hypertrophy can initially be viewed as a salutary response …
hemodynamic load. Although hypertrophy can initially be viewed as a salutary response …
Nitric oxide protects against pathological ventricular remodeling: reconsideration of the role of NO in the failing heart
SD Prabhu - Circulation research, 2004 - Am Heart Assoc
Nitric oxide (NO) is generated by NO synthases (NOSs) that convert L-arginine to L-citrulline
in the presence of molecular oxygen, nicotinamide-adenine dinucleotide phosphate …
in the presence of molecular oxygen, nicotinamide-adenine dinucleotide phosphate …
Relevance of nitric oxide for myocardial remodeling
PB Massion, JL Balligand - Current Heart Failure Reports, 2007 - Springer
Endogenous myocardial nitric oxide (NO) may modulate the transition from adaptive to
maladaptive remodeling leading to heart failure. In rodent models of pressure overload or …
maladaptive remodeling leading to heart failure. In rodent models of pressure overload or …
[PDF][PDF] Constitutive nitric oxide synthases in the heart from hypertrophy to failure.
X Loyer, C Heymes, JL Samuel - Clinical & Experimental …, 2008 - academia.edu
Endogenous myocardial nitric oxide (NO) may modulate the transition from adaptive to
maladaptive hypertrophy leading to heart failure. This review summarizes the information on …
maladaptive hypertrophy leading to heart failure. This review summarizes the information on …
Nitric oxide synthases in heart failure
R Carnicer, MJ Crabtree, V Sivakumaran… - Antioxidants & redox …, 2013 - liebertpub.com
Significance: The regulation of myocardial function by constitutive nitric oxide synthases
(NOS) is important for the maintenance of myocardial Ca2+ homeostasis, relaxation and …
(NOS) is important for the maintenance of myocardial Ca2+ homeostasis, relaxation and …
The role of nitric oxide in myocardial repair and remodeling
H Otani - Antioxidants & redox signaling, 2009 - liebertpub.com
Nitric oxide (NO) plays a crucial role in many aspects of the pathophysiology of heart failure.
NO is a double-edged sword; NO inhibits ischemia/reperfusion (I/R) injury, represses …
NO is a double-edged sword; NO inhibits ischemia/reperfusion (I/R) injury, represses …
Cardiomyocyte-specific overexpression of nitric oxide synthase 3: impact on left ventricular function and myocardial infarction
KD Bloch, S Janssens - Trends in Cardiovascular Medicine, 2005 - Elsevier
Identification of all three nitric oxide (NO) synthase (NOS) isoforms in cardiac myocytes and
the recognition of the importance of their subcellular localization have greatly advanced the …
the recognition of the importance of their subcellular localization have greatly advanced the …
Cardiomyocyte-specific overexpression of nitric oxide synthase 3 improves left ventricular performance and reduces compensatory hypertrophy after myocardial …
S Janssens, P Pokreisz, L Schoonjans… - Circulation …, 2004 - Am Heart Assoc
Nitric oxide (NO) is an important modulator of cardiac performance and left ventricular (LV)
remodeling after myocardial infarction (MI). We tested the effect of cardiomyocyte-restricted …
remodeling after myocardial infarction (MI). We tested the effect of cardiomyocyte-restricted …
Nitric oxide synthase in post-ischaemic remodelling: new pathways and mechanisms
B Manoury, V Montiel, JL Balligand - Cardiovascular research, 2012 - academic.oup.com
The three isoforms of nitric oxide synthase (NOS), spatially confined in specific intracellular
compartments in cardiac cells, have distinct roles in the regulation of contractility in …
compartments in cardiac cells, have distinct roles in the regulation of contractility in …
Regulation of the mammalian heart function by nitric oxide
PB Massion, M Pelat, C Belge, JL Balligand - … Biochemistry and Physiology …, 2005 - Elsevier
The mammalian heart expresses all three isoforms of nitric oxide synthases (NOS) in diverse
cell types of the myocardium. Despite their apparent promiscuity, the NOS isoforms support …
cell types of the myocardium. Despite their apparent promiscuity, the NOS isoforms support …