Cellular uptake and cytotoxicity of solid lipid nanospheres (SLN) incorporating doxorubicin or paclitaxel

A Miglietta, R Cavalli, C Bocca, L Gabriel… - International journal of …, 2000 - Elsevier
Solid Lipid Nanospheres (SLN) are colloidal therapeutic systems proposed for several
administration routes and obtained by dispersing warm microemulsions in cold water. SLN …

Pharmacokinetics of doxorubicin incorporated in solid lipid nanospheres (SLN)

GP Zara, R Cavalli, A FUNDARÒ, A Bargoni… - Pharmacological …, 1999 - Elsevier
The pharmacokinetics of doxorubicin incorporated as ion-pair into solid lipid nanospheres
(SLN) was compared with that of the commercial solution of the drug. Male albino rats …

Preparation and characterization of solid lipid nanoparticles loaded with doxorubicin

RK Subedi, KW Kang, HK Choi - European journal of pharmaceutical …, 2009 - Elsevier
Solid lipid nanoparticles (SLN) loaded with doxorubicin were prepared by solvent
emulsification-diffusion method. Glyceryl caprate (Capmul® MCM C10) was used as lipid …

Cytotoxicity of anticancer drugs incorporated in solid lipid nanoparticles on HT-29 colorectal cancer cell line

L Serpe, MG Catalano, R Cavalli, E Ugazio… - European Journal of …, 2004 - Elsevier
Solid lipid nanoparticles (SLN) carrying cholesteryl butyrate (chol-but), doxorubicin and
paclitaxel had previously been developed, and the antiproliferative effect of SLN …

Development and characterization of solid lipid nanoparticles loaded with a highly active doxorubicin derivative

B Stella, E Peira, C Dianzani, M Gallarate, L Battaglia… - Nanomaterials, 2018 - mdpi.com
Solid lipid nanoparticles (SLNs) comprise a versatile drug delivery system that has been
developed for the treatment of a variety of diseases. The present study will investigate the …

Non-stealth and stealth solid lipid nanoparticles (SLN) carrying doxorubicin: pharmacokinetics and tissue distribution after iv administration to rats

A Fundarò, R Cavalli, A Bargoni, D Vighetto… - Pharmacological …, 2000 - Elsevier
Non-stealth and stealth solid lipid nanoparticles (SLN) carrying doxorubicin were prepared
as drug delivery systems. The pharmacokinetics and tissue distribution of doxorubicin in …

[HTML][HTML] Solid lipid nanoparticles: An effective lipid-based technology for cancer treatment

M Akanda, MDSH Mithu, D Douroumis - Journal of Drug Delivery Science …, 2023 - Elsevier
Solid lipid nanoparticles (SLN) are considered at the forefront of nanotechnology's rapidly
developing field, with several potential applications in drug delivery and research. SLN …

Chemotherapy with anticancer drugs encapsulated in solid lipid nanoparticles

HL Wong, R Bendayan, AM Rauth, Y Li… - Advanced drug delivery …, 2007 - Elsevier
The prospect of improved cancer chemotherapy using solid lipid nanoparticles (SLN) as a
drug delivery system is promising. Several obstacles frequently encountered with anticancer …

Application of lipid microspheres for the treatment of cancer

M Takenaga - Advanced drug delivery reviews, 1996 - Elsevier
Lipid microspheres can act as a carrier for antitumor agents. We incorporated a lipophilic
antitumor agent, l, 3-bis (2-chloroethyl)-1-nitrosourea (BCNU) into microspheres by …

Cytotoxicity of solid lipid nanoparticles as a function of the lipid matrix and the surfactant

RH Müller, D Rühl, S Runge, K Schulze-Forster… - Pharmaceutical …, 1997 - Springer
Purpose. Assessment of the in vitro cytotoxicity of solid lipid nanoparticles (SLNs) as a
function of lipid matrix (Dynasan 114, Compritol ATO 888), and stabilizing surfactant …