Peripheral metabolic disturbances are associated with a variety of clinical health
consequences and may contribute to the development of neurocognitive disorders. This …

The prevalence of obesity and type 2 diabetes increases with age. Despite this, few studies
have examined these conditions simultaneously in aged animals, and fewer studies have …

While high‐fat diets are associated with rising incidence of obesity/type‐2 diabetes and can
induce metabolic and cognitive deficits, sex‐dependent comparisons are rarely …

Diabetes impacts on brain metabolism, structure, and function. Alterations in brain
metabolism have been observed in obesity and diabetes models induced by exposure to …

Excessive dietary fat intake is considered a great risk factor for metabolic disorders as well
as cognitive dysfunction. However, the potential mechanisms underlying the effects of a high …

Obesity arising from excessive dietary fat intake is a risk factor for cognitive decline,
dementia and neurodegenerative diseases, including Alzheimer's disease. Here, we studied …

The developing brain is sensitive to the impacts of early-life nutritional intake. This study
investigates whether maternal high fat diet (HFD) causes glucose metabolism impairment …

Background: The overconsumption of a high-fat diet (HFD) has been repeatedly blamed as
being a possible contributor to the global prevalence of emotional problems in modern …

Multiple factors of metabolic syndrome have been implicated in the pathogenesis of
Alzheimer's disease (AD), including abdominal obesity, insulin resistance, endocrine …

Obesity represents a risk factor for metabolic syndrome and cardiovascular and psychiatric
disorders. Excessive caloric intake, particularly in dietary fats, is an environmental factor that …