The ubiquitin-proteasome system and memory: moving beyond protein degradation
TJ Jarome, RK Devulapalli - The Neuroscientist, 2018 - journals.sagepub.com
Cellular models of memory formation have focused on the need for protein synthesis.
Recently, evidence has emerged that protein degradation mediated by the ubiquitin …
Recently, evidence has emerged that protein degradation mediated by the ubiquitin …
The ubiquitin-proteasome system and learning-dependent synaptic plasticity–A 10 year update
Over 25 years ago, a seminal paper demonstrated that the ubiquitin-proteasome system
(UPS) was involved in activity-dependent synaptic plasticity. Interest in this topic began to …
(UPS) was involved in activity-dependent synaptic plasticity. Interest in this topic began to …
Synaptic protein degradation in memory reorganization
BK Kaang, JH Choi - Synaptic Plasticity: Dynamics, Development and …, 2012 - Springer
The ubiquitin-proteasome system (UPS) is a ubiquitous, major pathway of protein
degradation that is involved in most cellular processes by regulating the abundance of …
degradation that is involved in most cellular processes by regulating the abundance of …
The role of the ubiquitin proteasome system in the memory process
Quite intuitive is the notion that memory formation and consolidation is orchestrated by
protein synthesis because of the synaptic plasticity necessary for those processes …
protein synthesis because of the synaptic plasticity necessary for those processes …
Local ubiquitin-proteasome-mediated proteolysis and long-term synaptic plasticity
The ubiquitin-proteasome pathway (UPP) of protein degradation has many roles in synaptic
plasticity that underlies memory. Work on both invertebrate and vertebrate model systems …
plasticity that underlies memory. Work on both invertebrate and vertebrate model systems …
Protein homeostasis and synaptic plasticity
IJ Cajigas, T Will, EM Schuman - The EMBO journal, 2010 - embopress.org
It is clear that de novo protein synthesis has an important function in synaptic transmission
and plasticity. A substantial amount of work has shown that mRNA translation in the …
and plasticity. A substantial amount of work has shown that mRNA translation in the …
The proteasome and epigenetics: zooming in on histone modifications
The proteasome is a structural complex of many proteins that degrades substrates marked
by covalent linkage to ubiquitin. Many years of research has shown a role for ubiquitin …
by covalent linkage to ubiquitin. Many years of research has shown a role for ubiquitin …
Synaptic plasticity: importance of proteasome-mediated protein turnover
H Cline - Current Biology, 2003 - cell.com
Synaptic Plasticity: Importance of Proteasome-Mediated Protein Turnover: Current Biology
Skip to Main Content Advertisement Current Biology This journal offers authors two options (open …
Skip to Main Content Advertisement Current Biology This journal offers authors two options (open …
The ubiquitin-proteasome pathway and synaptic plasticity
AN Hegde - Learning & memory, 2010 - learnmem.cshlp.org
Proteolysis by the ubiquitin-proteasome pathway (UPP) has emerged as a new molecular
mechanism that controls wide-ranging functions in the nervous system, including fine-tuning …
mechanism that controls wide-ranging functions in the nervous system, including fine-tuning …
Proteolysis, synaptic plasticity and memory
AN Hegde - Neurobiology of learning and memory, 2017 - Elsevier
Protein degradation has many critical functions in the nervous system such as refinement of
synaptic connections during development and synaptic plasticity and memory in the adult …
synaptic connections during development and synaptic plasticity and memory in the adult …