Nicotine enhances inhibition of mouse vagal motor neurons by modulating excitability of premotor GABAergic neurons in the nucleus tractus solitarii

H Xu, JA Boychuk, CR Boychuk… - Journal of …, 2015 - journals.physiology.org
The caudal nucleus of the solitary tract (NTS) serves as the site of the first synapse for
visceral sensory inputs to the central nervous system. The NTS sends functional projections …

Clinically-styled vagus nerve stimulation augments spontaneous discharge in second and higher order sensory neurons in rat nucleus of the solitary tract

E Beaumont, RBP Campbell… - American Journal …, 2017 - journals.physiology.org
Vagus nerve stimulation (VNS) currently treats patients with drug resistant epilepsy,
depression 26 and heart failure. The mild intensities used in chronic VNS suggest that …

Sensory afferent and hypoxia-mediated activation of nucleus tractus solitarius neurons that project to the rostral ventrolateral medulla

DD Kline, TL King, JR Austgen, CM Heesch… - Neuroscience, 2010 - Elsevier
The nucleus tractus solitarius (nTS) of the brainstem receives sensory afferent inputs,
processes that information, and sends projections to a variety of brain regions responsible …

The nucleus of the solitary tract and the coordination of respiratory and sympathetic activities

DB Zoccal, WI Furuya, M Bassi, DSA Colombari… - Frontiers in …, 2014 - frontiersin.org
It is well known that breathing introduces rhythmical oscillations in the heart rate and arterial
pressure levels. Sympathetic oscillations coupled to the respiratory activity have been …

Role of glutamate receptors in transmission of vagal cardiac input to neurones in the nucleus tractus solitarii in dogs

JL Seagard, C Dean, FA Hopp - The Journal of physiology, 1999 - Wiley Online Library
1 Vagal afferent input from cardiac mechanoreceptors excites neurones in the nucleus
tractus solitarii (NTS), but discharge patterns evoked by physiological activation of pressure …

Oxytocin and corticotropin‐releasing hormone exaggerate nucleus tractus solitarii neuronal and synaptic activity following chronic intermittent hypoxia

P Gama de Barcellos Filho, HA Dantzler… - The Journal of …, 2024 - Wiley Online Library
Chronic intermittent hypoxia (CIH) in rodents mimics the hypoxia‐induced elevation of blood
pressure seen in individuals experiencing episodic breathing. The brainstem nucleus tractus …

Depressed GABA and glutamate synaptic signaling by 5-HT1A receptors in the nucleus tractus solitarii and their role in cardiorespiratory function

TD Ostrowski, D Ostrowski… - Journal of …, 2014 - journals.physiology.org
Serotonin (5-HT), and its 5-HT1A receptor (5-HT1AR) subtype, is a powerful modulator of the
cardiorespiratory system and its sensory reflexes. The nucleus tractus solitarii (nTS) serves …

Excitatory amino acid transporters tonically restrain nTS synaptic and neuronal activity to modulate cardiorespiratory function

MP Matott, BC Ruyle, EM Hasser… - Journal of …, 2016 - journals.physiology.org
The nucleus tractus solitarii (nTS) is the initial central termination site for visceral afferents
and is important for modulation and integration of multiple reflexes including …

Activation of Phox2b-expressing neurons in the nucleus tractus solitarii drives breathing in mice

C Fu, L Shi, Z Wei, H Yu, Y Hao, Y Tian… - Journal of …, 2019 - Soc Neuroscience
The nucleus tractus solitarii (NTS) is implicated in the control of breathing, but the neuronal
phenotype and circuit mechanism involved in such a physiological function remain …

Chronic intermittent hypoxia affects integration of sensory input by neurons in the nucleus tractus solitarii

DD Kline - Respiratory physiology & neurobiology, 2010 - Elsevier
The autonomic nervous and respiratory systems, as well as their coupling, adapt over a wide
range of conditions. Chronic intermittent hypoxia (CIH) is a model for recurrent apneas and …