Disinhibition of the cardiac limb of the arterial baroreflex in rat: a role for metabotropic glutamate receptors in the nucleus tractus solitarii

AE Simms, JFR Paton… - The Journal of physiology, 2006 - Wiley Online Library
The nucleus tractus solitarii (NTS) is the first site of integration for primary baroreceptor
afferents, which release glutamate to excite second‐order neurones through ionotropic …

Targeted deletion of neurokinin-1 receptor expressing nucleus tractus solitarii neurons precludes somatosensory depression of arterial baroreceptor–heart rate reflex

JT Potts, AY Fong, PI Anguelov, S Lee, D McGovern… - Neuroscience, 2007 - Elsevier
Neurokinin-1 receptor (NK1-R) expressing neurons are densely distributed throughout the
nucleus tractus solitarii (NTS). However, their fundamental role in arterial baroreflex function …

Frequency‐dependent facilitation of synaptic throughput via postsynaptic NMDA receptors in the nucleus of the solitary tract

H Zhao, JH Peters, M Zhu, SJ Page… - The Journal of …, 2015 - Wiley Online Library
Key points Hindbrain NMDA receptors play important roles in reflexive and behavioural
responses to vagal activation. NMDA receptors have also been shown to contribute to the …

Glutamate release via NO production evoked by NMDA in the NTS enhances hypotension and bradycardia in vivo

I Matsuo, Y Hirooka, K Hironaga… - American Journal …, 2001 - journals.physiology.org
Nitric oxide (NO) in the nucleus tractus solitarii (NTS) plays an important role in regulating
sympathetic nerve activity. The aims of this study were to determine whether the activation of …

Involvement of glutamate in transmission of afferent constrictive inputs from the airways to the nucleus tractus solitarius in ferrets

MA Haxhiu, B Yamamoto, IA Dreshaj, D Bedol… - Journal of the autonomic …, 2000 - Elsevier
In this study, we identified the neurons within nucleus tractus solitarius (nTS) activated by
stimulation of airway sensory systems and examined the expression of AMPA receptor …

Chronic intermittent hypoxia alters glutamatergic control of sympathetic and respiratory activities in the commissural NTS of rats

JH Costa-Silva, DB Zoccal… - American Journal of …, 2012 - journals.physiology.org
Sympathetic overactivity and altered respiratory control are commonly observed after
chronic intermittent hypoxia (CIH) exposure. However, the central mechanisms underlying …

A‐type potassium channels differentially tune afferent pathways from rat solitary tract nucleus to caudal ventrolateral medulla or paraventricular hypothalamus

TW Bailey, SM Hermes, KL Whittier… - The Journal of …, 2007 - Wiley Online Library
The solitary tract nucleus (NTS) conveys visceral information to diverse central networks
involved in homeostatic regulation. Although afferent information content arriving at various …

H2O2 induces delayed hyperexcitability in nucleus tractus solitarii neurons

TD Ostrowski, EM Hasser, CM Heesch, DD Kline - Neuroscience, 2014 - Elsevier
Abstract Hydrogen peroxide (H 2 O 2) is a stable reactive oxygen species and potent
neuromodulator of cellular and synaptic activity. Centrally, endogenous H 2 O 2 is elevated …

The role of the paratrigeminal nucleus in vagal afferent evoked respiratory reflexes: a neuroanatomical and functional study in guinea pigs

AK Driessen, MJ Farrell, SB Mazzone… - Frontiers in …, 2015 - frontiersin.org
The respiratory tree receives sensory innervation from the jugular and nodose vagal sensory
ganglia. Neurons of these ganglia are derived from embryologically distinct origins and as …

Cellular heterogeneity within the solitary tract nucleus and visceral afferent processing—Electrophysiological approaches to discerning pathway performance

MC Andresen, TW Bailey, YH Jin, SJ McDougall… - Tzu Chi Medical …, 2007 - Elsevier
Many homeostatic reflexes depend on autonomic central nervous system mechanisms to
systemically coordinate visceral organ function. The nucleus of the solitary tract (NTS) is the …