In 1993, Malawi replaced chloroquine (CQ) with sulphadoxine‐pyrimethamine (SP) as its
first‐line treatment for uncomplicated malaria in children< 5 years of age. To assess the …

Summary In March 1993, sulphadoxine/pyrimethamine (SP) replaced chloroquine as the
first line drug for malaria treatment in Malawi. Since then, the Ministry of Health has been …

The increasing occurrence of chloroquine‐resistant Plasmodium falciparum in sub‐Saharan
Africa makes it essential to reconsider current recommendations for the treatment of …

The efficacy of sulfadoxine-pyrimethamine (SP) and amodiaquine (AQ) was assessed at
Kivunge and Micheweni in Zanzibar, Tanzania, in 2001. The main objective was to obtain …

The study examined the efficacy of chloroquine (CQ), amodiaquine (AQ) and sulphadoxine–
pyrimethamine (SP) for the treatment of uncomplicated Plasmodium falciparum malaria in …

OBJECTIVE: To evaluate the therapeutic efficacy of sulfadoxine-pyrimethamine,
amodiaquine, and the sulfadoxine-pyrimethamine-amodiaquine combination for the …

The safety and efficacy of amodiaquine (AQ), sulfadoxine-pyrimethamine (SP), and
coadministered AQ+ SP was assessed in 351 Tanzanian children (age range, 6-59 months) …

The rapid development of falciparum resistance to sulphadoxine–pyrimethamine (SP) in
East and Central Africa has raised concerns as to the efficacy of combining it with another …

Chloroquine can no longer be recommended as the first-line treatment for falciparum
malaria in several parts of Africa, given the increasing resistance of Plasmodium falciparum …

Since 1993 sulphadoxine/pyrimethamine (SP) has been used as the first‐line drug for
uncomplicated Plasmodium falciparum malaria in Malawi. To investigate the current efficacy …