Human pluripotent cells such as human embryonic stem cells (hESCs) and induced
pluripotent stem cells (iPSCs) and their in vitro differentiation models hold great promise for …

Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) hold tremendous
clinical potential because of their ability to self-renew, and to differentiate into all cell types of …

Pluripotent stem cells constitute a platform to model disease and developmental processes
and can potentially be used in regenerative medicine. However, not all pluripotent cell lines …

Embryonic stem cells (ESCs) first derived from the inner cell mass of blastocyst-stage
embryos have the unique capacity of indefinite self-renewal and potential to differentiate into …

Human embryonic stem cells (hESCs) share an identical genome with lineage-committed
cells, yet possess the remarkable properties of self-renewal and pluripotency. The diverse …

Although the concepts of somatic cell reprogramming and human‐induced pluripotent stem
cells (hiPSCs) generation have undergone several analyses to validate the usefulness of …

Embryonic stem cells are unique in their abilities of self-renewal and to differentiate into
many, if not all, cellular lineages. Transcriptional regulation, epigenetic modifications and …

The ability to culture pluripotent stem cells and direct their differentiation into specific cell
types in vitro provides a valuable experimental system for modeling pluripotency …

The revolutionary discovery that somatic cells can be reprogrammed by a defined set
transcription factors to induced pluripotent stem cells (iPSCs) changed dramatically the way …

Significance: Derived from the inner cell mass of the preimplantation embryo, embryonic
stem cells are prototype pluripotent stem (PS) cells that have the ability of self-renewal and …