[HTML][HTML] Permeabilizing cell membranes with electric fields
AA Aguilar, MC Ho, E Chang, KW Carlson, A Natarajan… - Cancers, 2021 - mdpi.com
Simple Summary The FDA recently approved a fourth approach (in addition to surgery,
radiation therapy, and chemotherapy) for treating glioblastoma; namely, tumor treating fields …
radiation therapy, and chemotherapy) for treating glioblastoma; namely, tumor treating fields …
[HTML][HTML] Tumor treating fields increases membrane permeability in glioblastoma cells
E Chang, CB Patel, C Pohling, C Young, J Song… - Cell death …, 2018 - nature.com
Glioblastoma is the most common yet most lethal of primary brain cancers with a one-year
post-diagnosis survival rate of 65% and a five-year survival rate of barely 5%. Recently the …
post-diagnosis survival rate of 65% and a five-year survival rate of barely 5%. Recently the …
[HTML][HTML] Current status of the preclinical evaluation of alternating electric fields as a form of cancer therapy
C Pohling, H Nguyen, E Chang, KE Schubert, Y Nie… - …, 2023 - Elsevier
Exposing cancer cells to alternating electric fields of 100-300 kHz frequency and 1-4 V/cm
strength has been shown to significantly reduce cancer growth in cell culture and in human …
strength has been shown to significantly reduce cancer growth in cell culture and in human …
Exploring the efficacy of tumor electric field therapy against glioblastoma: An in vivo and in vitro study
H Wu, L Yang, H Liu, D Zhou, D Chen… - CNS neuroscience & …, 2021 - Wiley Online Library
Aims Tumor electric fields therapy (TTFields) is emerging as a novel anti‐cancer
physiotherapy. Despite recent breakthroughs of TTFields in glioma treatment, the average …
physiotherapy. Despite recent breakthroughs of TTFields in glioma treatment, the average …
[PDF][PDF] Anti-cancer mechanisms of action of therapeutic alternating electric fields (tumor treating fields [TTFields])
S Shams, CB Patel - Journal of molecular cell biology, 2022 - academic.oup.com
Despite improved survival outcomes across many cancer types, the prognosis remains grim
for certain solid organ cancers including glioblastoma and pancreatic cancer. Invariably in …
for certain solid organ cancers including glioblastoma and pancreatic cancer. Invariably in …
[PDF][PDF] The mechanisms of action of Tumor Treating Fields
Abstract Tumor Treating Fields (TTFields), a new modality of cancer treatment, are electric
fields transmitted transdermally to tumors. The FDA has approved TTFields for the treatment …
fields transmitted transdermally to tumors. The FDA has approved TTFields for the treatment …
Tumor treating fields: a comprehensive overview of the underlying molecular mechanism
P Hong, N Kudulaiti, S Wu, J Nie… - Expert review of …, 2022 - Taylor & Francis
Introduction As a novel treatment modality, tumor treating fields (TTFields) exert low-
intensity, medium-frequency electric fields on tumor cells. TTFields' effectiveness and safety …
intensity, medium-frequency electric fields on tumor cells. TTFields' effectiveness and safety …
[HTML][HTML] Alternating Electric Fields (TTFields) Activate Cav1.2 Channels in Human Glioblastoma Cells
E Neuhaus, L Zirjacks, K Ganser, L Klumpp, U Schüler… - Cancers, 2019 - mdpi.com
Tumor treating fields (TTFields) represent a novel FDA-approved treatment modality for
patients with newly diagnosed or recurrent glioblastoma multiforme. This therapy applies …
patients with newly diagnosed or recurrent glioblastoma multiforme. This therapy applies …
Tumor treating fields: a novel treatment modality and its use in brain tumors
AF Hottinger, P Pacheco, R Stupp - Neuro-oncology, 2016 - academic.oup.com
Tumor treating fields (TTFields) are low-intensity electric fields alternating at an intermediate
frequency (200kHz), which have been demonstrated to block cell division and interfere with …
frequency (200kHz), which have been demonstrated to block cell division and interfere with …
[HTML][HTML] Tumor-treating fields in glioblastomas: past, present, and future
Simple Summary Glioblastoma (GBM) is the most common malignant primary brain tumor.
Although the standard of care, including maximal resection, concurrent radiotherapy with …
Although the standard of care, including maximal resection, concurrent radiotherapy with …