Adenosine A2B receptors as therapeutic targets
I Feoktistov, JN Wells, I Biaggioni - Drug development research, 1998 - Wiley Online Library
Recent evidence indicates that A2B receptors mediate cellular functions with potential
clinical relevance. Both A2A and A2B receptors mediate vasodilation, and the receptor type …
clinical relevance. Both A2A and A2B receptors mediate vasodilation, and the receptor type …
A2B Adenosine Receptors Stimulate Growth of Porcine and Rat Arterial Endothelial Cells
RK Dubey, DG Gillespie, EK Jackson - Hypertension, 2002 - Am Heart Assoc
The goal of this study was to determine which adenosine receptor subtype mediates growth
stimulation by adenosine in arterial endothelial cells. In porcine coronary artery and rat …
stimulation by adenosine in arterial endothelial cells. In porcine coronary artery and rat …
[HTML][HTML] The resurgence of A2B adenosine receptor signaling
CM Aherne, EM Kewley, HK Eltzschig - Biochimica et Biophysica Acta (BBA …, 2011 - Elsevier
Since its discovery as a low-affinity adenosine receptor (AR), the A2B receptor (A2BAR), has
proven enigmatic in its function. The previous discovery of the A2AAR, which shares many …
proven enigmatic in its function. The previous discovery of the A2AAR, which shares many …
The adenosine a2b receptor: its role in inflammation
J Ham, DA Rees - … Metabolic & Immune Disorders-Drug Targets …, 2008 - ingentaconnect.com
Investigations into the role of the adenosine A2b receptor have been enigmatic due to the
lack of good selective high affinity agonists and antagonists. Over the last few years several …
lack of good selective high affinity agonists and antagonists. Over the last few years several …
Adenosine A2B receptors
I Feoktistov, I Biaggioni - Pharmacological reviews, 1997 - ASPET
Adenosine is an endogenous nucleoside that modulates many physiological processes. Its
actions are mediated by interaction with specific cell membrane receptors. Four subtypes of …
actions are mediated by interaction with specific cell membrane receptors. Four subtypes of …
A2B Receptors Mediate Antimitogenesis in Vascular Smooth Muscle Cells
RK Dubey, DG Gillespie, H Shue, EK Jackson - Hypertension, 2000 - Am Heart Assoc
Adenosine inhibits growth of vascular smooth muscle cells. The goals of this study were to
determine which adenosine receptor subtype mediates the antimitogenic effects of …
determine which adenosine receptor subtype mediates the antimitogenic effects of …
Adenosine A1 receptors and vascular reactivity
Y Wang, JN Yang, A Arner, PJM Boels… - Acta …, 2010 - Wiley Online Library
Aim: Blood pressure is higher in A1 receptor knock‐out (A1R−/−) mice than in wild type litter
mates (A1R+/+) and we have examined if this could be related to altered vascular functions …
mates (A1R+/+) and we have examined if this could be related to altered vascular functions …
Role of A2A adenosine receptors in inflammation
GW Sullivan, J Linden - Drug Development Research, 1998 - Wiley Online Library
ABSTRACT A2A adenosine receptors are expressed on immune cells including neutrophils,
lymphocytes, eosinophils, monocytes/macrophages, and mast cells. Activation of A2A …
lymphocytes, eosinophils, monocytes/macrophages, and mast cells. Activation of A2A …
Role of adenosine A2B receptors in inflammation
I Feoktistov, I Biaggioni - Advances in pharmacology, 2011 - Elsevier
Recent progress in our understanding of the unique role of A 2B receptors in the regulation
of inflammation, immunity, and tissue repair was considerably facilitated with the introduction …
of inflammation, immunity, and tissue repair was considerably facilitated with the introduction …
The A3 adenosine receptor: an enigmatic player in cell biology
Adenosine is a primordial signaling molecule present in every cell of the human body that
mediates its physiological functions by interacting with 4 subtypes of G-protein-coupled …
mediates its physiological functions by interacting with 4 subtypes of G-protein-coupled …