Recent evidence indicates that A2B receptors mediate cellular functions with potential
clinical relevance. Both A2A and A2B receptors mediate vasodilation, and the receptor type …

The goal of this study was to determine which adenosine receptor subtype mediates growth
stimulation by adenosine in arterial endothelial cells. In porcine coronary artery and rat …

Since its discovery as a low-affinity adenosine receptor (AR), the A2B receptor (A2BAR), has
proven enigmatic in its function. The previous discovery of the A2AAR, which shares many …

Investigations into the role of the adenosine A2b receptor have been enigmatic due to the
lack of good selective high affinity agonists and antagonists. Over the last few years several …

Adenosine is an endogenous nucleoside that modulates many physiological processes. Its
actions are mediated by interaction with specific cell membrane receptors. Four subtypes of …

Adenosine inhibits growth of vascular smooth muscle cells. The goals of this study were to
determine which adenosine receptor subtype mediates the antimitogenic effects of …

Aim: Blood pressure is higher in A1 receptor knock‐out (A1R−/−) mice than in wild type litter
mates (A1R+/+) and we have examined if this could be related to altered vascular functions …

ABSTRACT A2A adenosine receptors are expressed on immune cells including neutrophils,
lymphocytes, eosinophils, monocytes/macrophages, and mast cells. Activation of A2A …

Recent progress in our understanding of the unique role of A 2B receptors in the regulation
of inflammation, immunity, and tissue repair was considerably facilitated with the introduction …

Adenosine is a primordial signaling molecule present in every cell of the human body that
mediates its physiological functions by interacting with 4 subtypes of G-protein-coupled …