Asthma is an inflammatory disorder principally involving the conducting airways and
characterised by infiltration of the airway wall with a range of inflammatory cells driven in …

The adoption of the concept that asthma is primarily a disease most frequently associated
with elaboration of T‐helper 2 (Th2)‐type inflammation has led to the widely held concept …

Asthma is a genetically and phenotypically complex disease that has a major impact on
global health. Signs and symptoms of asthma are caused by the obstruction of airflow …

While asthma is an inflammatory disorder of the airways involving mediator release from
mast cells and eosinophils and orchestrated by T cells, inflammation alone is insufficient to …

Asthma is a chronic inflammatory disorder of the airways manifesting as intermittent airflow
limitation, which over time may become progressive (1). Both in the allergic and nonallergic …

Asthma is an inflammatory disorder of the airways dominated by a Th2-type pattern.
Because of this, most research has focused on investigating the role of allergic pathways …

The aims of this article are to understand the shortfalls in thinking of asthma purely as an
atopic disorder, to gain insight into the epithelial abnormalities of asthma and how these …

Although asthma is an inflammatory disorder of the conducting airways involving TH2-type T
cells, there is increasing evidence for an important role played by the epithelium in …

Epithelial cells in the airway wall actively interact with environmental antigens/allergens,
both in healthy individuals and patients with asthma. In patients with (allergic) asthma, the …

Asthma is a chronic inflammatory airway disease characterized by variable airflow
obstruction in response to a wide range of exogenous stimuli. The airway epithelium is the …