Hyperphosphatemia is a common complication in patients with chronic kidney disease
(CKD), particularly in those requiring renal replacement therapy. The importance of …

Background Whether phosphate itself has nephrotoxicity in patients with chronic kidney
disease (CKD) is controversial, although phosphate excretion into urine may cause tubular …

Chronic kidney disease (CKD)–mineral and bone disorder is associated with diverse
metabolic and endocrine disturbances that ultimately may contribute to further loss of kidney …

Hyperphosphataemia occurs in nearly all patients with end-stage renal disease (ESRD). In
the past, the need to manage hyperphosphataemia focused primarily on its role as a …

Cardiovascular disease has been associated with elevated serum phosphorus levels, which
have been associated with cardiovascular mortality. This is commonly seen in the chronic …

Elevated Cardiac Markers in Chronic Kidney Disease as a Consequence of
Hyperphosphatemia-Induced Cardiac Myocyte Injury - PMC Back to Top Skip to main content NIH …

Intracellular phosphate is critical for cellular processes such as signaling, nucleic acid
synthesis, and membrane function. Extracellular phosphate (Pi) is an important component …

Cardiovascular (CV) disease is the commonest cause of mortality in patients with chronic
kidney disease (CKD). Vascular calcification (VC), induced by calcium and phosphate …

Serum phosphate independently predicts cardiovascular mortality in the general population
and CKD, even when levels are in the normal range. Associations between serum …

BACKGROUND: Serum phosphorus is associated with cardiovascular disease (CVD) in the
general population, but may not comprehensively reflect phosphorus homeostasis. Whether …