There is a strong association between increased blood concentrations of low-density
lipoprotein (LDL) and severity of coronary atherosclerosis. Multiple mechanisms affect …

The low density lipoprotein particle is the major transporter of cholesterol around the body
and has been shown to be a strong independent risk factor for atherosclerotic events. This …

Low density lipoprotein (LDL) is probably the most atherogenic of all the lipoproteins.
Several abnormalities in LDL metabolism seem to be associated with coronary heart …

Both cholesterol esters (CE) and triacylglycerols (TG) are insoluble in water (plasma); hence
they are packaged as lipoproteins comprising an inner core of CE and TG with a surface …

Recent studies have shown that heterogeneity of human plasma low-density lipoproteins
(LDL) is, in part, the result of production of different LDL products from two subspecies of …

The plasma lipoproteins are the primary means of transport of cholesterol among tissues. In
particular, the apo B-containing lipoproteins (VLDL, IDL and LDL) are important for the …

Modified forms of low density lipoprotein (LDL) are associated with increased atherogenicity.
Modified LDL, in comparison with native LDL, demonstrates enhanced cellular uptake by …

Background The fact that low density lipoprotein (LDL) 1 is extremely susceptible to
oxidative damage has been known for some time (1, 2), but until quite recently this was …

Measurement of serum lipoproteins by analytic ultracentrifugation revealed significant
correlations involving subfractions of low density (LDL) and high density (HDL) lipoproteins …

A variety of epidemiologic, biochemical, and experimental studies have established a direct
relationship between low density lipoprotein (LDL) cholesterol concentration and the risk of …