A sensitive and specific HPLC-MS method for the determination of sophoridine, sophocarpine and matrine in rabbit plasma

Y Wu, J Chen, Y Cheng - Analytical and bioanalytical chemistry, 2005 - Springer
A sensitive and specific method was developed for the determination of sophoridine (SRI),
sophocarpine (SC) and matrine (MT) in rabbit plasma by HPLC-MS. After an administration …

HPLC simultaneous separation and determination of sophoridine, matrine, oxymatrine, sophoramine, sophocarpine

A ZHANG, Y ZHANG - Chinese Journal of Pharmaceutical …, 2008 - ingentaconnect.com
To establish an HPLC method for the simultaneous determination of sophoridine, matrine,
oxymatrine, sophoramine, sophocarpine. Method: Determination research was taken with …

A rapid reversed phase high-performance liquid chromatographic method for determination of sophoridine in rat plasma and its application to pharmacokinetics …

Y Wei, X Wu, X Liu, J Luo - Journal of Chromatography B, 2006 - Elsevier
A high-performance liquid chromatography (HPLC) method for determining sophoridine in
rat plasma was developed for application in the pharmacokinetic studies. The plasma was …

Determination of sophoricoside in rat plasma by HPLC and its application to pharmacokinetic studies

R Luo, Z Li, G Qian, J Lu, C Fu - Yakugaku Zasshi, 2009 - jstage.jst.go.jp
A simple, sensitive, selective and reproducible reversed-phase HPLC method was
developed for the determination of sophoricoside in rat plasma after intravenous …

High‐performance liquid chromatographic method for simultaneous determination of sophoridine and matrine in rat plasma

Y Li, G Min, Q Xue, L Chen, W Liu… - Biomedical …, 2004 - Wiley Online Library
A high-performance liquid chromatographic (HPLC) method is described for the
simultaneous determination of sophoridine and matrine in rat plasma. Sophoridine and …

HPLC simultaneous determination of the contents of sophoridine, matrine and sophocarpine in total alkaloid of Sophora alopecuroides L.

B XIANG - Chinese Journal of Pharmaceutical Analysis, 2006 - ingentaconnect.com
To establish an HPLC method for simultaneous determination of the contents of sophoridine,
matrine and sophocarpine in total alkaloid of Sophora alopecuroides L. Method …

Simultaneous determination of matrine, oxysophocarpin and oxymatrine in rat plasma by HPLC-MS and its application in the pharmacokinetic study

L Zhang, ZW Wang, JW Lian, H Zhou… - Yao xue xue bao …, 2008 - europepmc.org
To establish an HPLC-MS method for simultaneous determination of matrine, oxymatrine
and oxysophocarpine in rat plasma after oral administration of herbal preparation, namely …

Pharmacokinetics and excretion study of sophoricoside and its metabolite in rats by liquid chromatography tandem mass spectrometry

X Zhi, N Sheng, L Yuan, Z Zhang, P Jia, X Zhang… - … of Chromatography B, 2014 - Elsevier
In this study, a new liquid chromatography–tandem mass spectrometry (LC–MS/MS) method
has been developed and validated for the determination of sophoricoside and its metabolite …

An UPLC-MS/MS method for determination of solasonine in rat plasma and its application of a pharmacokinetic and bioavailability study

Y Chen, S Zhang, D Chen, M Zhou, J Zheng… - … of Chromatography B, 2015 - Elsevier
Solasonine, a known glycoalkaloid, is a potential anti-cancer agent. In this work, a simple,
sensitive and fast ultra performance liquid chromatography with tandem mass spectrometry …

Establishment of quantitative methodology for sophoridine analysis and determination of its pharmacokinetics and bioavailability in rat

M Chen, Q Jiang, M Zhang, S Chen, J Lou… - Drug Development …, 2021 - Taylor & Francis
Objective The aim of this study is to develop a rapid and sensitive UPLC–MS/MS approach
to determine the sophoridine (SOP) level in rat plasma and the pharmacokinetics of the …