Purpose Osteoarthritis (OA) is a joint disease that is clinically diagnosed using components
of history, physical exam, and characteristic radiographic findings, such as joint space …

Objectives A narrative review on recent published studies of metabolomics in osteoarthritis
(OA) with the focus on how the metabolomic findings help stratify OA patients in precision …

Abstract Purpose of the Review Osteoarthritis (OA) is a multifactorial and progressive
disease affecting whole synovial joint. The extract pathogenic mechanisms and diagnostic …

OA is a multifactorial and progressive disease with no cure yet. Substantial efforts have been
made and several biochemical and genetic markers have been reported, but neither alone …

Osteoarthritis (OA) represents the most prevalent and disabling arthritis worldwide due to its
heterogeneous and progressive articular degradation. However, effective and timely …

Osteoarthritis (OA) is a progressive, deteriorative disease of articular joints. Although
traditionally viewed as a local pathology, biomarker exploration has shown that systemic …

Objective A systematic review and analysis of data from several rheumatoid arthritis
metabolomics studies attempts to determine which metabolites can be used as potential …

January 2013, Vol 21, No 1 63 was more hypoxic and acidotic than in the normal joint and
that arthritic joints may rely in part on altered lipid metabolic pathways. We have performed …

Increasing evidence implicates metabolic dysfunction in the development and progression
of osteoarthritis (OA). Large-scale'omics' studies, particularly metabolomics, have the …

Sir Archibald Edward Garrod, who pioneered the field of inborn errors of metabolism and
first elucidated the biochemical basis of alkaptonuria over 100 years ago, suggested that …