Cationic solid lipid nanoparticles (SLN) have recently been suggested for non-viral gene
delivery, as these particles consist of well tolerated substances, can bind DNA directly via …

The suitability of cationically modified solid-lipid nanoparticles (SLN) as a novel transfection
agent was investigated. SLN were produced by hot homogenisation using either Compritol …

Solid lipid nanoparticles (SLNs) have been proposed in the 1990s as appropriate drug
delivery systems, and ever since they have been applied in a wide variety of cosmetic and …

In this paper, the suitability of novel cationic solid-lipid nanoparticles (SLN) as a nonviral
transfection agent for gene delivery was investigated. SLN were produced by using the …

Cationic solid lipid nanoparticles (SLN) can bind DNA directly via ionic interaction and
mediate in vitro gene transfection. However, toxicity is still an obstacle, which is strongly …

Cationic solid lipid nanoparticles (SLN) are promising nonviral gene delivery carriers
suitable for systemic administration. The objective of this study was to investigate the …

Gene transfer represents an important advance in the treatment of both genetic and
acquired diseases. In this article, the suitability of cationically modified solid-lipid …

DNA vaccination has been extensively studied as a promising strategy for tumor treatment.
Despite the efforts, the therapeutic efficacy of DNA vaccines has been limited by their …

Importance of the field: Gene therapy represents a new paradigm in the prevention and
treatment of many inherited and acquired diseases, including genetic disorders, such as …

In recent years, nanomaterials have been widely applied as advanced drug and gene
delivery nanosystems. Among them, solid lipid nanoparticles (SLNs) have attracted great …