Introduction: The development and potential clinical use of tissue-selective androgen
receptor modulators (SARMs) have advanced tremendously over the past few years. A key …

Selective androgen receptor modulators (SARMS) bind to the androgen receptor and
demonstrate anabolic activity in a variety of tissues; however, unlike testosterone and other …

Selective androgen receptor modulators (SARMs) are small molecule drugs that function as
either androgen receptor (AR) agonists or antagonists. Variability in AR regulatory proteins …

Background: Selective androgen receptor modulators (SARMs) represent a new class of
pharmaceuticals that may find wide clinical use. However, selectivity is not understood at the …

Interest in the development and therapeutic potential of nonsteroidal tissue-selective
androgen receptor modulators (SARMs) a has increased dramatically within the past …

Abstract The Androgen Receptor (AR), a member of the steroid hormone receptor family,
plays important roles in the physiology and pathology of diverse tissues. AR ligands, which …

Androgen receptor (AR) plays a critical role in the function of several organs including
primary and accessory sexual organs, skeletal muscle, and bone, making it a desirable …

Selective androgen receptor modulators (SARMs) are a novel class of androgen receptor
(AR) ligands that might change the future of androgen therapy dramatically. With improved …

Modulation of the androgen receptor has the potential to be an effective treatment for
hypogonadism, andropause, and associated conditions such as sarcopenia, osteoporosis …

Androgens are essential for male development and the maintenance of male secondary
characteristics, such as bone mass, muscle mass, body composition, and spermatogenesis …