Weekly docetaxel versus docetaxel/gemcitabine in the treatment of elderly or poor performance status patients with advanced nonsmall cell lung cancer: a …

JD Hainsworth, DR Spigel, C Farley, DL Shipley… - Cancer, 2007 - Wiley Online Library
BACKGROUND. The aim of this study was to compare the efficacy of single‐agent weekly
docetaxel with the combination of docetaxel and gemcitabine in elderly and/or poor …

Combination treatment with weekly docetaxel and gemcitabine for advanced non–small-cell lung cancer in elderly patients and patients with poor performance status …

JD Hainsworth, JB Erland, JH Barton, DS Thompson… - Clinical Lung Cancer, 2003 - Elsevier
The purpose of this study was to evaluate the feasibility, toxicity, and efficacy of the
combination of weekly docetaxel and gemcitabine in patients with advanced non–small-cell …

Weekly docetaxel as a single agent and in combination with gemcitabine in elderly and poor performance status patients with advanced non-small cell lung cancer

JD Hainsworth, HA Burris III, FA Greco - Seminars in oncology, 2001 - Elsevier
Administering docetaxel weekly at a relatively low dose minimizes myelosuppression and
reduces nonhematologic toxicities. In a community-based phase II trial conducted in 39 …

Randomized phase III trial comparing weekly docetaxel plus cisplatin versus docetaxel monotherapy every 3 weeks in elderly patients with advanced non–small-cell …

T Abe, K Takeda, Y Ohe, S Kudoh… - Journal of Clinical …, 2015 - ascopubs.org
Purpose This phase III trial aimed to confirm the superiority of weekly docetaxel and cisplatin
over docetaxel monotherapy in elderly patients with advanced non–small-cell lung cancer …

[HTML][HTML] A randomized phase II trial of two schedules of docetaxel in elderly or poor performance status patients with advanced non-small cell lung cancer

R Lilenbaum, M Rubin, J Samuel, L Boros… - Journal of Thoracic …, 2007 - Elsevier
Background: We conducted a multicenter randomized phase II trial to evaluate two
schedules of single-agent docetaxel in the first-line treatment of elderly and performance …

Weekly docetaxel in the treatment of elderly patients with advanced nonsmall cell lung carcinoma: a Minnie Pearl Cancer Research Network phase II trial

JD Hainsworth, HA Burris III, S Litchy… - … Journal of the …, 2000 - Wiley Online Library
BACKGROUND Weekly administration of docetaxel was found to reduce myelosuppression
and other nonhematologic toxicities when compared with administration every 3 weeks. In …

[HTML][HTML] First line chemotherapy with weekly docetaxel and cisplatin in elderly patients with advanced non-small cell lung cancer: a multicenter phase II study

K Han, W Cao, J Che, S Bo, X Guo, G Huang… - Journal of Thoracic …, 2009 - Elsevier
Introduction We report outcomes for a phase II study of the combination of weekly docetaxel
and cisplatin in elderly patients with advanced non-small cell lung cancer. Methods Patients …

An open multicenter phase II trial of weekly docetaxel for advanced-stage non-small-cell lung cancer in elderly patients with significant comorbidity and/or poor …

H LeCaer, F Barlesi, G Robinet, P Fournel, L Geriniere… - Lung Cancer, 2007 - Elsevier
CONTEXT: The objective of this study was to evaluate the feasibility and activity of weekly
docetaxel monotherapy in frail elderly patients with advanced-stage non-small-cell lung …

A phase II randomized trial of docetaxel weekly or every 3 weeks in elderly and/or poor performance status (PS) patients (pts) with advanced non-small cell lung …

R Lilenbaum, M Rubin, J Samuel, L Boros… - Journal of Clinical …, 2004 - ascopubs.org
7057 Background: Docetaxel has been used in elderly and PS 2 pts with advanced NSCLC
with acceptable toxicity. However, myelosuppression can be severe on the every 3-week …

Phase III study of docetaxel compared with vinorelbine in elderly patients with advanced non–small-cell lung cancer: Results of the West Japan Thoracic Oncology …

S Kudoh, K Takeda, K Nakagawa, M Takada… - Journal of Clinical …, 2006 - ascopubs.org
Purpose Docetaxel has shown activity in elderly patients with advanced non–small-cell lung
cancer (NSCLC). This randomized phase III trial evaluated the efficacy and safety of …