Spermatozoon is a cell with a precious message to deliver: the paternal DNA. Its motility
machinery must be working perfectly and it should be able to acquire fertilizing ability in …

Oxidative stress plays a major role in the life and death of mammalian spermatozoa. These
gametes are professional generators of reactive oxygen species (ROS), which appear to …

The male factor is considered a major contributory factor to infertility. Apart from the
conventional causes for male infertility such as varicocoele, cryptorchidism, infections …

Nearly 15% of couples experience infertility as a universal health issue. About 50% of
infertility cases have been known to be associated with the male partner. Oxidative stress …

Reactive oxygen species (ROS) generated at low levels during mitochondrial respiration
have key roles in several signaling pathways. Oxidative stress (OS) arises when the …

Infertility is a relatively common condition affecting approximately one in ten of the
population. In half of these cases, a male factor is involved, making defective sperm function …

Male fertility is affected by multiple endogenous stressors, including reactive oxygen species
(ROS), which greatly deteriorate the fertility. However, physiological levels of ROS are …

Current evidence links oxidative stress (OS) to male infertility, reduced sperm motility, sperm
DNA damage and increased risk of recurrent abortions and genetic diseases. A review of …

The pathophysiology of male infertility involves various interlinked endogenous pathways.
About 50% of the cases of infertility in men are idiopathic, and oxidative stress (OS) …

Highly reactive oxygen radicals such as the superoxide anion (* 0;>, the hydroxyl radical (.
OH), and the hypochlorite radical (* OHCl) comprise what is called the reactive oxygen …