Neutrophils are the most abundant circulating and first-responding innate myeloid cells and
have so far been underestimated in the context of multiple sclerosis (MS). MS is the most …

Multiple sclerosis (MS) is a demyelinating disease of the central nervous system with a
strong autoimmune, neurodegenerative, and neuroinflammatory component. Most of the …

Neutrophils are the first line of defense in the innate immune system, helping to maintain
tissue homeostasis as well as eliminating pathogens and self-components. The traditional …

Multiple sclerosis (MS) is believed to be initiated when myelin-specific T cells infiltrate the
central nervous system (CNS), triggering subsequent recruitment of inflammatory leukocytes …

Neutrophils are armed with proteases with indiscriminate histotoxic potential, and to
minimize tissue injury, their activation involves priming with inflammatory mediators before …

Inflammatory diseases involve numerous disorders and medical conditions defined by an
insufficient level of self-tolerance. These diseases evolve over the course of a multi-step …

Introduction Neutrophils are the key cells of our innate immune system with a primary role in
host defense. They rapidly arrive at the site of infection and display a range of effector …

In the past, neutrophils were often reduced to their ability to release preformed mediators
and kill pathogens. The present volume of Chemical Immunology and Allergy, however …

Neutrophils are the most abundant of the circulating immune cells and are the first to be
recruited to sites of inflammation. Neutrophils are a heterogeneous group of immune cells …

Neutrophils were long considered to be a short-lived homogenous cell population, limited to
their role as first responders in anti-bacterial and-fungal immunity. While it is true that …