Highlights•Mass spectrometric imaging is a new imaging tool.•It is also a new technique
available for pharmacokinetics studies.•Images of molecular distribution inside tissues slices …

Over the last decade mass spectrometry imaging (MSI) has been integrated in to many
areas of drug discovery and development. It can have significant impact in oncology drug …

Since its introduction mass spectrometry imaging (MSI) has proven to be a powerful tool for
the localization of molecules in biological tissues. In drug discovery and development …

Failure of systemic cancer treatment can be, at least in part, due to the drug not being
delivered to the tumour at sufficiently high concentration and/or sufficiently homogeneous …

In the last decade mass spectrometry imaging has developed rapidly, in terms of multiple
new instrumentation innovations, expansion of target molecules, and areas of application …

Mass spectrometry imaging (MSI) has seen remarkable development in recent years. The
possibility of getting quantitative or semiquantitative data, while maintaining the spatial …

Foreword Oppenheimer & Wehr to radiolabeling. As our ability to process large quantities of
data improve, 3D imaging and high-resolution imaging of larger specimens will allow us to …

Mass spectrometry imaging (MSI) is a rapidly evolving technology that yields qualitative and
quantitative distribution maps of small pharmaceutical-active molecules and their …

MALDI mass spectrometry imaging (MSI) provides a technology platform that allows the
accurate visualization of unlabeled small molecules within the two-dimensional spaces of …

Understanding the biodistribution, metabolism and accumulation of drugs in the body is a
fundamental of pharmaceutical research and development. Mass Spectrometry imaging …