Agonist and antagonist effects of the putative P2Y1 receptor antagonist adenosine 3′-
phosphate 5′-phosphosulphate (PAPS) were studied in intact tissues. In the carbachol …

We previously reported a structure–activity study which identified Acid blue 129 (1‐amino‐4‐
(2, 4, 6‐trimethylphenylamino)‐9, 10‐dioxo‐9, 10‐dihydroanthracene‐2‐sulfonic acid) as a …

Nucleotides regulate various effects including vascular tone. This study was aimed to
characterize P2Y receptors on endothelial cells of the aorta of C57BL6 mice. Five adjacent …

Substantial evidence documents the potential importance of P2Y receptor subtypes in the
regulation of cellular responses, but few selective antagonists exist for these receptors. In …

P2Y1receptor-like responses were analyzed in rat ileal myocytes and in rat brain capillary
endothelial cells. In endothelial cells, pyridoxal phosphate-6-azophenyl-2′, 4′ disulfonic …

The receptors through which 2-methylthio ATP (MeSATP), adenosine 5′-O-(2-
thiodiphosphate)(ADPβS), UTP and ATP elicit endothelium-dependent relaxation of …

The functional activity of deoxyadenosine 5′(α‐thio) triphosphate (dATPαS) was assessed
at the cloned human P2Y1 receptor stably expressed in 1321N1 human astrocytoma cells …

The agonist selectivity for adenosine di-and triphosphates was determined for the human
P2Y1 receptor stably expressed in human 1321N1 astrocytoma cells and was studied under …

Background and Purpose Acyl derivatives of CoA have been shown to act as antagonists at
human platelet and recombinant P2Y1 receptors, but little is known about their effects in the …

Pulmonary vascular tone is modulated by nucleotides, but which P2 receptors mediate these
actions is largely unclear. The aim of this study, therefore, was to use subtype-selective …