During the past few decades, great strides have been made to treat life-threatening diseases
such as cancer, diabetes, and cardiovascular disease. A main outcome of these …

The classification of neurodegenerative disorders includes human diseases that vary
significantly in terms of their incidence, clinical presentation, and prognosis. All of these …

Factors associated with predisposition and vulnerability to neurodegenerative disorders may
be described usefully within the context of gene-environment interplay. There are many …

Neurodevelopmental disorders are generally influenced by not only genetic, but also
intrauterine and extrauterine factors that affect the fetal-maternal environment and/or brain …

In the present review we summarize recent advances in the understanding of the interaction
between genetics and environmental factors involved in complex multi-factorial …

Neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD),
Amyotrophic lateral sclerosis (ALS) and retinal degeneration have been studied extensively …

Neurodegenerative diseases affect millions of people globally and are characterized by their
poor prognosis and decreased quality of life. In the quest to shed light on the development …

As the human population lives longer, so diseases of the elderly and aging are thrown into
sharp focus. Chronic progressive degenerative diseases of the central nervous system …

Non-cancer degenerative diseases are a complex and heterogeneous mix of different
diseases sharing a complex and long-lasting pathogenesis resulting in irreversible cell loss …

Most neurodegenerative diseases have a relatively minor genetic component. Huntington's
disease is the only major exception, with the genetic penetrance being 100%. This implies …